Results 121 to 130 of about 2,709,505 (306)

Applying Graph Theory to Examine the Dynamics of Student Discussions in Small-Group Learning. [PDF]

, 2019
Group work in science, technology, engineering, and mathematics courses is an effective means of improving student outcomes, and many different factors can influence the dynamics of student discussions and, ultimately, the success of collaboration.
Chai, Albert, Le, Joshua P, Lee, Andrew S, Lo, Stanley M   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

A peer group intervention implemented by community volunteers increased HIV prevention knowledge. [PDF]

BMC Public Health, 2023
Kumbani LC, Jere DL, Banda CK, Chang C, Liu L, McCreary LL, Patil CL, Norr KF.   +7 more
europepmc   +1 more source

Attainment in Secondary School [PDF]

This paper studies attainment in secondary schools. We estimate an education production function in which attainment depends upon parental inputs, peer group inputs and schooling inputs.
James Symons, L Feinstein
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A research synthesis of effective programs to address gender-based violence in the school context: actors involved, and impacts achieved

Frontiers in Education
Gender-based violence is a social problem that is also present in schools. Scientific research on violence in the school setting has discussed schools as a context of socialization on gender violence, but also as a context where gender violence ...
Silvia Molina Roldán, Tatiana íñiguez-Berrozpe, Ana Inés Renta-Davids, Elsa Cerviño-López   +3 more
doaj   +1 more source

How do peer group reflection meetings support medical students' learning and personal development during clinical rotations? [PDF]

BMC Med Educ, 2023
van den Eertwegh V, Stalmeijer RE.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

“Why Are You Happy if Your Dad Died?”: The Social Experiences of Parentally Bereaved Children in Elementary and Middle Schools

Children
Background: Parental loss in childhood is a significant developmental risk factor, underscoring the need for evidence-based knowledge to guide support. Although social responses play a central role in children’s adjustment to loss, little is known about ...
Yael Boutton-Laor, Yulia Muchnik-Rozanov, Rivi Frei-Landau   +2 more
doaj   +1 more source