Results 161 to 170 of about 959,546 (306)

Use of context-awareness in mobile peer-to-peer networks

, 2001
Mobile ad-hoc network are an emerging research field due to the potential range of applications that they support and for the problems they present due to their dynamic nature. Peer-to-peer is an example of a class of applications that have recently been
Mascolo, C, Gold, R
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effectiveness of a peer group-based online intervention program in empowering families of children with disabilities at home. [PDF]

Front Pediatr, 2022
Wakimizu R, Matsuzawa A, Fujioka H, Nishigaki K, Sato I, Suzuki S, Iwata N.   +6 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Chinese Singaporean Children's Expectations About Peer Group Norms in the Context of Wealth and Ethnicity. [PDF]

Dev Sci
Paquette A, Singh L, Forbes MB, Killen M.   +3 more
europepmc   +1 more source

The role of gender in peer-group perceptions of climate scientists' media statements. [PDF]

Public Underst Sci, 2021
Armstrong L, Adamson G.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Relationship of Peer Support and Learning Motivation among Nursing Students in Aceh, Indonesia

JLUMHS
OBJECTIVE: The study aims to investigate the relationship between peer support and learning motivation among nursing students at Universitas Syiah Kuala (USK).
Arfiza Ridwan, Nur Sabina Zulhijjah, Sarini Vivi Yanti   +2 more
doaj   +1 more source

Academic achievement of peer group leaders and members: Contributions to adolescents' social, school, and psychological adjustment. [PDF]

J Res Adolesc
Zhou J, Chen X, Li D, Liu J, Cui L, Liu S.   +5 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source