Results 91 to 100 of about 558,691 (303)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Detecting Malicious Peers in Overlay Multicast Streaming
, 2008 Overlay multicast streaming is built out of loosely coupled end-hosts (peers) that contribute resources to stream media to other peers. Peers, however, can be malicious.
Ying Cai +3 more
core
Adolescents Spending Time with Their Parents: Does It Matter?
YouthThe current study aims to explore the relevance of ‘time spent with parents’ for different risk behaviors (i.e., alcohol use, smoking, gambling and problematic social media use), peer factors (i.e., time spent with peers, peer pressure and peer support ...
Ina Koning, Carmen Voogt
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Too Good for the Gays: Douglas Stuart’s “The Englishman”
Journal of the Short Story in English“Too Good for the Gays” is a creative-critical essay stemming from a book-length project-in-progress titled A Fuckable Object. A Fuckable Object is a critical memoir (a term borrowed from Jill Dolan and Ann Cvetkovich) which examines the author’s ...
Darryl Peers
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Under Pressure? The Effect of Peers on Outcomes of Young Adults [PDF]
A variety of public campaigns, including the “Just Say No” campaign of the 1980s and 1990s that encouraged teenagers to “Just Say No to Drugs”, are based on the premise that teenagers are very susceptible to peer influences.
Kjell G Salvanes +2 more
core +6 more sources
نشریه پرستاری ایران, 1993 This is a cross sectional study with aim of assessment and comparison between parents and female adolescents ' attitudes about the role of peers in decision making of adolescent in Tehran.
A Ebrahimi +3 more
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source