Results 81 to 90 of about 558,691 (303)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

On the stability of BDMS and PEERS elements

, 2007
Using "Fortin operators" we give a new proof of stability for Stenberg's family of BDMS elements in linear elasticity. Our approach yields the inf-sup condition with respect to the standard norms, which is indispensable for a posteriori
Peers Elements, Marco Lonsing, Rüdiger Verfürth   +2 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Majority group children expect that ethnic out-group peers feel fewer positive but more negative emotions than in-group peers [PDF]

, 2018
Across two studies majority group children’s (8–13 years) perception of positive and negative emotions in ethnic in-group and disadvantaged ethnic out-group peers was examined. Study 1 (N = 302) showed that children expected in-group peers to feel better
Sierksma, Jellie; id_orcid, Jellie Sierksma (5985527), Sierksma, J., Bijlstra, G., Bijlstra, Gijsbert, Gijsbert Bijlstra (5812883)   +5 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Opinion Dynamics: the Effect of the Number of Peers Met at Once [PDF]

The opinion dynamics model introduced by Deffuant and Weisbuch as well as the one by Hegselmann and Krause are rather similar. In both models individuals are assumed to have opinions about an issue, they meet and discuss, and they may adapt their ...
Diemo Urbig, Jan Lorenz, Heiko Herzberg
core  

Eating disorders in pediatric population, analysis of some of the most common risk factors

Journal of Education, Health and Sport
Introduction: This article reviews a number of studies that have sought to determine what are risk factors that may cause eating disorders in the pediatric population, taking into account the age and gender of the subjects.
Magdalena Czeczotka, Marta Skorupska, Natalia Aleksandra Popławska, Justyna Śliz, Krzysztof Woźniak   +4 more
doaj   +1 more source