Results 301 to 310 of about 1,932,841 (382)

Enhanced brain delivery of oleanolic acid by GSH-PEGylated liposomes and its amelioration of scopolamine-induced cognitive dysfunction via multi-target regulation. [PDF]

Int J Pharm X
Luo Y, Hong X, Chen X, Liang Y, Li F, Shi X, Huang X.   +6 more
europepmc   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Efficacy and acceptability of bowel preparation strategies for inflammatory bowel disease colonoscopy: Systematic review and meta-analysis. [PDF]

Endosc Int Open
Nigam GB, Gordon M, Sinopoulou V, Tomar A, Din S, Vance M, Wilson A, East JE, British Society of Gastroenterology Colorectal IBD Surveillance Guideline Development Group .   +8 more
europepmc   +1 more source

Functional Metal Complexes for Solar–Light‐Driven Energy Conversion

Advanced Materials, EarlyView.
This review provides an exhaustive summary of the recent advancements of functional metal complexes in solar‐to‐electrical, ‐chemical, and ‐thermal energy conversion, comprising material categories, design strategies, underlying principles of operation, and identified improvement of performances.
Yanyan Qin, Dou Luo, Miao Zhang, Wai‐Yeung Wong   +3 more
wiley   +1 more source

Hydrogelation via Supramolecular Copolymerization of Structural Water within Adaptive Metal–Organic Fibers

Advanced Materials, EarlyView.
Structural water is harnessed as an active co‐monomer to drive supramolecular polymerization in bulk water. Zinc(II) Salphen complexes confine water molecules to form hollow, metal–organic nanofibers that assemble into adaptive hydrogels with thermoresponsive mechanics and selective chiral recognition.
Merlin R. Stühler, Hesam Makki, Tarek Hilal, Debsena Chakraboty, Mathias Dimde, Kai Ludwig, Rainer Haag, Sabine Rosenfeldt, Dorothee Silbernagl, Andreas Schäfer, Alex J. Plajer   +10 more
wiley   +1 more source

E-Selectin-Targeted Nanomicelles via Sialic Acid Conjugation for Anti-Inflammatory Efficacy and Alleviating the Progression of Metabolic-Associated Steatotic Liver Disease. [PDF]

Biomater Res
Zhang C, Zhang C, Sun Q, Wu H, Yin W, Zhu H, Huang S, Zhang Z, Zou Y, Wen D, Xu X, Lian M, Sun C, Tai S.   +13 more
europepmc   +1 more source

PBAE-PEG/LipidNanoparticle Delivery of RNA for theCreation of Genetically Engineered Lung Cancer Mouse Models

Bingxin Liu (1734601), William D. Stuart (15150480), Iris M. Fink-Baldauf (15150483), Elisa Boscolo (14925429), Mari Mino-Kenudson (55973), Eric L. Snyder (15069189), Yutaka Maeda (360088)   +6 more
openalex   +1 more source

Oxygen‐Inhibition Driven Compartmentalization of Dextran Microgels: Toward Fusible Colloidal Biomaterial Inks for 3D Printing

Advanced Materials, EarlyView.
Harnessing oxygen inhibition as a materials design principle enables the universal fabrication of core–shell microgels with tunable radial crosslinking gradients. This conceptually simple yet highly versatile strategy generates fusible colloidal bioinks that combine structural hierarchy with adaptive porosity.
Selin Bulut, Thomas Bissing, Tudor Lile, Hannah Küttner, Daniel Günther, Cédric Bergerbit, Dan Eugen Demco, Laura De Laporte, Andrij Pich   +8 more
wiley   +1 more source