Results 321 to 330 of about 1,932,841 (382)
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Stealth nanoparticles in oncology: Facing the PEG dilemma.
Journal of Controlled Release, 2022Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not only pharmacokinetic properties of the encapsulated agent, but also providing a significant protection of the drug from non-desired interactions, and reducing side-
S. Zalba +3 more
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PEG-based thermosensitive and biodegradable hydrogels.
Acta Biomaterialia, 2021Injectable thermosensitive hydrogels are free-flowing polymer solutions at low or room temperature, making them easy to encapsulate the therapeutic payload or cells via simply mixing.
Jiayue Shi, Lin Yu, Jiandong Ding
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Biomaterials, 2020
Although synergistic therapy for tumors has displayed significant promise for effective treatment of cancer, developing a simple and effective strategy to build a multi-functional nanoplatform is still a huge challenge.
Man Wang +8 more
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Although synergistic therapy for tumors has displayed significant promise for effective treatment of cancer, developing a simple and effective strategy to build a multi-functional nanoplatform is still a huge challenge.
Man Wang +8 more
semanticscholar +1 more source
International journal of pharmaceutics, 2020
PEGylation-modification with polyethylene glycol (PEG)-is useful for stabilizing lipid nanoparticles (LNPs). However, such PEGylation can prevent small interfering RNA (siRNA) encapsulated in LNPs from exerting its gene-silencing effects by disrupting ...
Takuya Suzuki +8 more
semanticscholar +1 more source
PEGylation-modification with polyethylene glycol (PEG)-is useful for stabilizing lipid nanoparticles (LNPs). However, such PEGylation can prevent small interfering RNA (siRNA) encapsulated in LNPs from exerting its gene-silencing effects by disrupting ...
Takuya Suzuki +8 more
semanticscholar +1 more source
Expert Opinion on Pharmacotherapy, 2007
L-asparaginases have been established components in the treatment of acute leukemias for nearly 40 years. Their antitumor effect results from the depletion of asparagine, an amino acid essential to leukemic cells, and subsequent inhibition of protein synthesis leading to considerable cytotoxicity.
Cecilia H, Fu, Kathleen M, Sakamoto
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L-asparaginases have been established components in the treatment of acute leukemias for nearly 40 years. Their antitumor effect results from the depletion of asparagine, an amino acid essential to leukemic cells, and subsequent inhibition of protein synthesis leading to considerable cytotoxicity.
Cecilia H, Fu, Kathleen M, Sakamoto
openaire +2 more sources
Caprolactonic Poloxamer Analog: PEG-PCL-PEG
Biomacromolecules, 2005The aqueous solution of poly(ethylene glycol)-poly(caprolactone)-poly(ethylene glycol) (PEG-PCL-PEG) triblock copolymers (> 15. wt. %) undergoing "clear sol-gel-turbid sol" transition as the temperature increases from 20 to 60 degrees C has been developed.
Min Ji, Hwang +4 more
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International journal of pharmaceutics, 2019
&NA; Non‐healing wounds are among the serious complications of type‐2‐diabetes around the globe, associated with high incidence of bacterial infection, chronic nerve and blood vessel damage, and eventually repeated amputation of limbs and organs.
N. Masood +8 more
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&NA; Non‐healing wounds are among the serious complications of type‐2‐diabetes around the globe, associated with high incidence of bacterial infection, chronic nerve and blood vessel damage, and eventually repeated amputation of limbs and organs.
N. Masood +8 more
semanticscholar +1 more source