Results 91 to 100 of about 6,454,817 (367)

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Preparation of nanofibrous poly (L-lactic acid) scaffolds using the thermally induced phase separation technique in dioxane/polyethylene glycol solution

Designed Monomers and Polymers, 2023
Porous nanofibrous poly (L-lactic acid) (PLLA) scaffolds were fabricated in combination with a thermally induced phase separation technique using a dioxane/polyethylene glycol (PEG) system.
Tao Zhang, Kangyao Chen, Xing Wu, Xiufeng Xiao   +3 more
doaj   +1 more source

On X-ray Optical Depth in the Coronae of Active Stars

, 2007
We have investigated the optical thickness of the coronal plasma through the analysis of high-resolution X-ray spectra of a large sample of active stars observed with the High Energy Transmission Grating Spectrometer on Chandra.
Berdyugina S. V., Berdyugina S. V., Berdyugina S. V., David P. Huenemoerder, Favata F., Favata F., Giovanni Peres, Jeremy J. Drake, Kaastra J. S., Kashyap V., Maggio A., Mewe R., Mitrou C. K., Paola Testa, Phillips K. J. H., Schuessler M., Strassmeier K. G.   +16 more
core   +1 more source

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

A Comparison of JPEG and Wavelet Compression Applied to CT Images [PDF]

, 2003
A study of image compression is becoming more important since an uncompressed image requires a large amount of storage space and high transmission bandwidth.
Ng, Kwan Hoong, Ramli, Abdul Rahman, Saffor, Amhamed   +2 more
core  

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Coronal properties of the EQ Peg binary system

, 2008
The activity indicators of M dwarfs are distinctly different for early and late types. The coronae of early M dwarfs display high X-ray luminosities and temperatures, a pronounced inverse FIP effect, and frequent flaring to the extent that no quiescent ...
A. Maggio, Acton, Asplund, Benedict, Brosius, Browning, C. Liefke, Chabrier, Chabrier, Delfosse, Dobler, Drake, Durney, Favata, Feldman, Fleming, Fuhrmeister, Güdel, Güdel, Güdel, Haisch, Hawley, J. H. M. M. Schmitt, J.-U. Ness, Jackson, Kenyon, Kron, Lacy, Landi, Liefke, Liefke, Linsky, Magee, Maggio, Maggio, Mahmoud, Mazzotta, Monsignori Fossi, Mullan, Ness, Ness, Ness, Ness, Ness, Ness, Ness, Nordon, Nordon, Norton, Osten, Osten, Pallavicini, Pallavicini, Parker, Parkinson, Parsamyan, Pettersen, Pettersen, Pizzolato, Raassen, Reiners, Robrade, Robrade, Rutledge, Sanz-Forcada, Schmitt, Schmitt, Schmitt, Schmitt, Spiesman, Stelzer, Stelzer, Telleschi, Testa, Testa, Torres, Torres, Vaiana, van den Besselaar, Yildiz, Zboril, Zuckerman   +81 more
core   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

Simple Bedside Predictors of Survival after Percutaneous Gastrostomy Tube Insertion

Canadian Journal of Gastroenterology and Hepatology, 2019
Background. Percutaneous endoscopic gastrostomy (PEG) tube insertion is an increasingly used minimally invasive method for long-term enteral feeding. Identification of simple predictors for short-term mortality (up to one month) after PEG insertion is of
Wisam Sbeit, Anas Kadah, Amir Mari, Mahmud Mahamid, Tawfik Khoury   +4 more
doaj   +1 more source