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Successful Treatment of Granulocyte Colony‐Stimulating Factor‐Related Aortitis in Prostate Cancer [PDF]

IJU Case Reports
Introduction The frequency of granulocyte colony‐stimulating factor‐related aortitis is low. We report a case of successful corticosteroid treatment in a patient with prostate cancer who developed aortitis following pegfilgrastim administration.
Shota Yamada, Kota Amamoto, Nobuhide Maekawa, Kazusato Hara, Takahisa Iwata, Yushi Imasato, Tomohiro Matsuo, Masataka Furukawa, Ryoichi Imamura   +8 more
doaj   +3 more sources

Efficacy and Safety of Pegfilgrastim in Patients With Severe Congenital Neutropenia [PDF]

eJHaem
Background Severe congenital neutropenia (SCN) is commonly treated with granulocyte colony‐stimulating factor (G‐CSF) to reduce neutropenia and the associated risk of infections.
Mahdiyeh Movahedi, Leila Moradi, Zahra Alizadeh, Mojtaba Tabatabaei Yazdi, Shirin Dehbashi, Raheleh Shokouhi Shoormasti, Marzieh Maddah, Anahita Razaghian, Amir Ali Hamidieh, Mansoureh Shariat, Massoud Houshmand, Atefe Alirezaee, Maryam Akbari, Mohammad Reza Fazlollahi, Zahra Pourpak   +14 more
doaj   +3 more sources

Impact of single dose of pegfilgrastim on peripheral blood stem cell harvest in patients with multiple myeloma or malignant lymphoma [PDF]

Scientific Reports
This phase 2 study evaluated the impact of pegfilgrastim, a single-dose, long-acting granulocyte colony-stimulating factor, on the steady-state mobilization of hematopoietic stem cells into peripheral blood in patients with multiple myeloma (MM) or ...
Hideki Goto, Masashi Sawa, Shin-ichiro Fujiwara, Masaki Ri, Tadao Ishida, Masahiro Takeuchi, Kenji Ishitsuka, Masako Toyosaki, Kazutaka Sunami, Junichi Tsukada, Takashi Sonoki, Aiko Shimogomi, Yuki Ichihashi, Yoshiumi Ouchi, Toshihiro Miyamoto, Masayuki Hino, Yoshinobu Maeda, Takanori Teshima   +17 more
doaj   +2 more sources

Successful Treatment of Neutropenia Associated With T-Cell Large Granular Lymphocytic Leukemia Using Fludarabine. [PDF]

Case Rep Hematol
T‐cell large granular lymphocytic leukemia (T‐LGLL) is an uncommon lymphoproliferative disorder that typically follows a slow clinical course. Symptoms often remain subtle until cytopenia or infection develops. Severe infection secondary to neutropenia represents the major cause of mortality.
Uemura Y, Togitani K, Kumon Y.
europepmc   +2 more sources

Medical visits for chemotherapy and chemotherapy-induced neutropenia: a survey of the impact on patient time and activities [PDF]

BMC Cancer, 2004
Background Patients with cancer must make frequent visits to the clinic not only for chemotherapy but also for the management of treatment-related adverse effects.
Moore Kelley, Okon Theodore A, Zhu Ling, Tauer Kurt, Fortner Barry V, Templeton Davis, Schwartzberg Lee   +6 more
doaj   +4 more sources

A Case of Pegfilgrastim-Induced Sweet Syndrome and Literature Review of Similar Cases

Case Reports in Oncological Medicine
Sweet's syndrome (SS), also known as acute febrile neutrophilic dermatosis, is a rare disorder characterized by painful erythematous lesions, fever, and neutrophilic dermal infiltrates.
Meghana Kesireddy, Olivia L. Makos, Dominick J. DiMaio, Jairam Krishnamurthy   +3 more
doaj   +2 more sources

Pegfilgrastim

Reactions Weekly
Patel P, King N, Jacobs TF.
europepmc   +9 more sources

Demonstration of Physicochemical and Functional Similarity of Biosimilar Pegfilgrastim-cbqv to Pegfilgrastim [PDF]

Drugs in R&D
Background Pegfilgrastim-cbqv/CHS-1701 (UDENYCA®) (hereafter referred to as pegfilgrastim-cbqv) was approved in 2018 by the US Food and Drug Administration as a biosimilar for pegfilgrastim (Neulasta®) (hereafter referred to as pegfilgrastim).
Henriette Kuehne, Janice M. Davis, LeeAnne Merewether, Matthew McQueen, Elizabeth Valentine, Glen Young, Benjamin T. Andrews, Dimitri Diaz, Karen J. Miller   +8 more
doaj   +2 more sources

Radiation emergency medical countermeasures: Current formulary, identified gaps, and future approaches. [PDF]

Animal Model Exp Med
Current radiation medical countermeasures primarily focus on hematopoietic acute radiation syndrome (H‐ARS) using agents like granulocyte colony‐stimulating factor (G‐CSF), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), and romiplostim, alongside treatments for internal contamination (Prussian blue, diethylenetriamine pentaacetate [DTPA ...
Ma WB, Yin RH, Ren GM, Zhang Y, Li LJ, Liu W, Chen T, Zhou W, Zu M, Yin RL, Shi XD, Wang L, Yang XM.   +12 more
europepmc   +2 more sources

Pegfilgrastim-related thoracic aortitis: A case report and literature review

Current Problems in Cancer: Case Reports, 2023
Pegfilgrastim can prevent febrile neutropenia during chemotherapy and helps maintain treatment intensity. Aortitis is a rare and serious adverse event associated with pegfilgrastim therapy. The mechanism of pegfilgrastim-related aortitis is unknown.
Chikako Sekine, Sasagu Kurozumi, Hirotoshi Kawashima, Koichi Hirose, Jun Horiguchi   +4 more
doaj   +1 more source