Lenograstim in preventing chemotherapy-induced febrile neutropenia in patients with soft tissue sarcoma [PDF]
Background: Neutropenia and its complications represent one of the principal dose-limiting toxicity issues in chemotherapeutic regimens for soft tissue sarcoma.
BADALAMENTI, Giuseppe +6 more
core
Cost Effectiveness of First-Line Treatment with Doxorubicin/Ifosfamide Compared to Trabectedin Monotherapy in the Management of Advanced Soft Tissue Sarcoma in Italy, Spain, and Sweden [PDF]
BACKGROUND: Doxorubicin/ifosfamide is a first-line systemic chemotherapy for the majority of advanced soft tissue sarcoma (ASTS) subtypes. Trabectedin is indicated for the treatment of ASTS after failure of anthracyclines and/or ifosfamide; however it is
Gough, N +4 more
core +2 more sources
Chemotherapeutic agent 5-fluorouracil increases survival of SOD1 mouse model of ALS [PDF]
Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease with no cure. Currently there are only two ALS drugs approved by the FDA, both with a limited therapeutic effect.
Hernández i Estanyol, Sara +8 more
core +7 more sources
Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy [PDF]
Despite great medical advancement in the treatment of cancer, cancer remains a disease of global significance. Chemotherapeutics can be very expensive and drain medical resources at a national level and in some cases the cost of treatment is so great ...
Foster, Neil +2 more
core +3 more sources
PCN46 EPOIETIN ALPHA TREATMENT FOR CANCER PATIENTS WITH CHEMOTHERAPY INDUCED ANAEMIA–A COSTEFFECTIVENESS ANALYSIS FOR SWEDEN [PDF]
Saturday, 5th June ...
Borg, S, Glenngård, AH, Persson, U
core +1 more source
This randomized, open‐label, active‐controlled study investigated the safety and efficacy of three doses of Rolontis (eflapegrastim), a novel, long‐acting myeloid growth factor, versus pegfilgrastim in breast cancer patients being treated with docetaxel ...
Jeffrey L. Vacirca +19 more
doaj +1 more source
Leukopenia Associated with Long-Term Colchicine Adminsitration [PDF]
Purpose A case of leukopenia in a patient receiving colchicine for calcium pyrophosphate dihydrate deposition disease, or pseudogout, is reported. Summary An 85-year-old man experienced leukopenia likely due to colchicine. His medical history included
Beggs, Ashton E. +2 more
core +1 more source
A 75‐year‐old woman with stage IVB (cT3N3M1c) extensive disease small‐cell lung cancer was treated with carboplatin, etoposide, and atezolizumab. Ten days after pegfilgrastim initiation, during the second chemotherapy cycle, she experienced back pain ...
Keisuke Shiraha +13 more
doaj +1 more source
An Exploratory Analysis of Pharmaceutical Price Disparities and Their Implications Among Six Developed Nations [PDF]
In our study of 43 drugs, prescription drug prices in several wealthy nations (Australia, Canada, France, Germany, and the U.K.) were much lower than in the U.S. on average, well below relative per capita GDP. There was relatively little difference among
Calfee, John E. +2 more
core +1 more source
Prophylaxis of infectious complications with colony-stimulating factors in adult cancer patients undergoing chemotherapy—evidence-based guidelines from the Infectious Diseases Working Party AGIHO of the German Society for Haematology and Medical Oncology (DGHO) [PDF]
We found convincing evidence from numerous randomised controlled trials that G-CSF, biosimilar G-CSF and pegfilgrastim reduce the risk to develop febrile neutropenia and infections.
Bohlius, J. +11 more
core

