DNA Origami Uptake in Y‐79 Retinoblastoma Cells Driven by Oligolysine Coating
We show that polymeric coating can enable DNA origami nanoparticle internalization into ocular retinoblastoma cells. Not only are the coated nanoparticles well‐tolerable to the cells, but they also remain mobile in the vitreous of a porcine ex vivo model.
Anna Klose +8 more
wiley +1 more source
Surface Functionalization Studies in the Development of Nanohole Plasmonic Sensors. [PDF]
Sayin S +4 more
europepmc +1 more source
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
Porcine interferon-alpha but not interferon-lambda inhibits replication of genotypically diverse PRRSV isolates <i>in vitro</i>. [PDF]
Hau SJ +5 more
europepmc +1 more source
Upon contact with plasma, lipid nanoparticles (LNPs) rapidly acquire a protein corona (PC) that redefines their biological identity. In calcium‐containing environments, these coronated particles trigger the formation of a gel‐like plasma network, profoundly altering their transport properties and reducing their effective availability.
Serena Renzi +14 more
wiley +1 more source
Solvent Reorganization in Stabilized Protein-Polymer Conjugates Visualized by Two-Dimensional Infrared and Nuclear Magnetic Resonance Spectroscopy. [PDF]
Maia R +4 more
europepmc +1 more source
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Cysteine Pegylation of a Mutant L-asparaginase Affords Enhanced Activity and Thermostability. A Comparative Study Against N-terminal Conjugation. [PDF]
Ferraro RB +11 more
europepmc +1 more source
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi +3 more
wiley +1 more source
Beneficial Hepatokines in MASLD/MASH: Therapeutic Potentials and Drug Delivery Challenges. [PDF]
Amatya R, Min KA, Shin MC.
europepmc +1 more source

