Results 201 to 210 of about 22,067 (275)

Accuracy of Factor VIII Assays for Measuring Damoctocog Alfa Pegol: A Comparative Analysis

Haemophilia, Volume 32, Issue 5, Page 1282-1287, September/October 2026.
ABSTRACT Introduction Accurate monitoring of treatment with modified factor VIII products remains challenging, due to known variability in assay performance across different laboratory methods and reagents. For the extended half‐life product Damoctocog alfa pegol discrepancies have been reported.
Judith C. A. Cluitmans, Piet Meijer, Sanna R. Rijpma, An K. Stroobants   +3 more
wiley   +1 more source

Multiscale Computational Studies of PEG Chain Length Effects on HER2 mAb Fc Structure and Binding Energetics. [PDF]

ACS Omega
Noriega HA, Akala EO, Wang XS.
europepmc   +1 more source

Therapeutic Potential of Gene‐Modified MSC‐Exos in Insulin Resistance: Mitochondrial Crosstalk and miRNA Regulation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Insulin resistance (IR) is the key driver of type 2 diabetes mellitus, metabolic dysfunction‐associated steatotic liver disease, and cardiometabolic disorders. Mesenchymal stem cell‐derived exosomes (MSC‐Exos) as a potent cell‐free alternative can deliver miRNAs, proteins, and mitochondrial regulators to reactivate the IRS1/PI3K/Akt/GLUT4 axis.
Qinghua Jia, Bing Li, Yuan Xing, Yuanyuan Zhang, Baodong Gao, Xiangying Li, Xiaoqin Ha   +6 more
wiley   +1 more source

Silver nanoparticle-induced site-specific strand cleavage of chemically modified oligonucleotides for long-chain DNA assembly. [PDF]

Nucleic Acids Res
Inagaki M, Kase M, Hiraoka H, Oka N, Hashiya F, Abe N, Kimura Y, Abe H.   +7 more
europepmc   +1 more source

Covalent "Locking" of Prodrug Nanoassemblies via Thiol-Ene Click Crosslinking for Potent Antitumor Therapy. [PDF]

Adv Healthc Mater
Li X, Li L, Zhao Y, Cui J, Zhang L, Sun J, Sun B.   +6 more
europepmc   +1 more source

Integrative Peptide Drug Development: Chemical Engineering, AI-Driven Design, and Cell-Penetrating Peptides. [PDF]

Pharmaceutics
Jang YE, Kwon M, Kwon CW, Kim SG, Hwang JS, George NP, Paik SR, Misra S, Basith S, Sheen SS, Lee G.   +10 more
europepmc   +1 more source

Circulating PEG-indoleamine 2,3-dioxygenase ameliorates diverse inflammatory diseases without toxicity or compromising immunocompetence. [PDF]

Proc Natl Acad Sci U S A
Simonovich JA, Clark RA, Kwiatkowski AJ, Fuchs MJ, Viso ME, Lu C, Macias SL, Pinto I, Shrestha AP, Ngo TB, Duarte S, He Y, Hu Q, Lu G, Hartman JB, Su G, Scali ST, Berceli SA, Sharma AK, Upchurch GR, Islam S, Wanchoo A, Hudalla GA, Robinson ST, Zarrinpar A, Avram D, Keselowsky BG.   +26 more
europepmc   +1 more source

GLP-1 and GIP class drugs have neuroprotective properties in Alzheimer's and Parkinson's disease. [PDF]

Front Neurosci
Hölscher C.
europepmc   +1 more source

PEGylated thymosin β4 is a thiol-site-specific prodrug treating myocardial infarction in vivo. [PDF]

Bioeng Transl Med
Peng H, Chai Y, Gong C, Hao Y, Peng Y, Zhang W, Liu X, Tang S, Kong Q, Wang Q.   +9 more
europepmc   +1 more source

Evaluation of Human Serum Albumin Nanoparticles for Rapamycin Delivery. [PDF]

ACS Omega
Rodero CF, Pangua C, Gracia JM, Suner MB, Guiguer MT, Chorilli M, Irache JM.   +6 more
europepmc   +1 more source