Results 101 to 110 of about 557,698 (316)
Acta Polytechnica, 2005 The importance of fuel reliability is growing due to the deregulated electricity market and the demands on operability and availability to the electricity grid of nuclear units.
M. Dostál, J. Zymák, M. Valach
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Factors affecting wood, energy grass and straw pellet durability – A review [PDF]
, 2017 Pellets produced from wood, energy grasses and straw present a higher energy density feedstock than wood chips or bales, and therefore reduce the costs of handling, transport and storage throughout the supply chain. European specifications provide limits
Whittaker, C. +3 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
, 2010 To investigate the behavior of a plasmoid consisting of pellet ablatant ionized by background plasma, two dimensional imaging measurements of high-speed spectroscopy have been developed using a fast camera in the Large Helical Device (LHD).
YAMADA, Hiroshi +4 more
core +1 more source
Acceleration of Cryogenic Pellets for Shattered Pellet Injection
Fusion Engineering and Design, 2023 Á. Kovács +13 more
openaire +2 more sources