Results 101 to 110 of about 790,408 (311)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Quantitative spore recoveries from diatomaceous earth pellets used as protective material in dry heat sterilization studies [PDF]

Quantitative spore recoveries from diatomaceous earth pellets used to simulate electronic components in dry heat sterilization ...
Portner, D. M.
core   +1 more source

Effect of composition of fuel pellets on their quality parameters [PDF]

, 2013
The present researches are aimed at studying the influence of composite pellets on their quality measures. To obtain experimental samples of pellets, we used the main tree species of wood, that is pine, alder and birch.
Khmyzov, I. A., Solovyeva, T. V., Sychova, N. A.   +2 more
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Processing of Secondary Raw Materials from Ferrochrome Production via Agglomeration and Study of Their Mechanical Properties

Metals
In the process of producing ferroalloys, a large amount of secondary raw materials is formed, including slag, aspiration dusts and sludge. The recycling of secondary raw materials can create resources and bring environmental and economic benefits.
Yerlan Zhumagaliyev, Yerbol Shabanov, Maral Almagambetov, Maulen Jundibayev, Nursultan Ulmaganbetov, Salamat Laikhan, Akgul Jundibayeva, Aigerim Abilberikova, Nurbala Ubaidulayeva, Rysgul Adaibayeva   +9 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Characteristics of Chitosan Derived from Lobster Shells and its Effect on Fungi Activity and Water Stability of Lobster Pellets

Jurnal Ilmiah Perikanan dan Kelautan
Graphical Abstract   Highlights of Research • The chitosan was successfully produced from lobster shells Panulirus homarus. • The characteristics and quality of chitosan from lobster shells Panulirus homarus were observed.
Muhsinul Ihsan, Ali Harris, Mukminah, Megawati, Nining Purwati, Handa Muliasari, Bayu Priyambodo, Clive Jones, Leo Nankervis   +8 more
doaj   +1 more source

Feasibility study on isostatic pressing of pyrrones Final report [PDF]

Compression molding technique for manufacturing Pyrrone pellets by isostatic ...
Bradbury, E. J., Dunnavant, W. R.
core   +1 more source