Results 41 to 50 of about 560,758 (346)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Economic and ecological advantages of innovative project implementation at woodworking industry
Trudy Odesskogo Politehničeskogo Universiteta, 2015 Orientation to innovative development involves the strategic focus onto manufacturing high-tech products in the priority sectors of the economy. Implementation of innovative projects aimed at reducing the energy component in overall costs of enterprise ...
Irina N. Yepifanova +2 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Energies, 2021 The need to increase the use of renewable biomasses for energy supply, such as fuel pellets is significant. However, different types of biomasses have different mechanical properties to be pelletized, which entails a limitation in available raw materials
Stefan Frodeson +6 more
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
On the Use of Transfer Entropy to Investigate the Time Horizon of Causal Influences between Signals
Entropy, 2018 Understanding the details of the correlation between time series is an essential step on the route to assessing the causal relation between systems.
Andrea Murari +7 more
doaj +1 more source
Influence of SiO2 on the Compressive Strength and Reduction-Melting of Pellets
Metals, 2019 The effects of SiO2 content on the compressive strength, reduction behavior and melting-dripping properties of the pellets were investigated under experimental conditions.
He Guo +5 more
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Waste and Biomass Valorization, 2018 The aims of the study were (a) the determination of the physicochemical characteristics of properties of pellets made of shredded residue from hay, wheat straw, and their blend at a ratio of 50:50, and (b) the determination of a mathematical model of ...
A. Lisowski +7 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source