Results 61 to 70 of about 438,568 (317)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Energy Analysis of Pellets Made of Wood Residues

open access: yesCroatian Journal of Forest Engineering, 2008
The use of high technology in the manufacture of pellets and their use in modern furnace chambers of boiler plants for remote heating and heating of family houses, are the reason why pellets as the energy source find an ever increasing application.
Stjepan Risović   +2 more
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Properties of pellets made of desintegrated phyto-raw-materials [PDF]

open access: yesActa Montanistica Slovaca, 2002
The utilization of wastes and the so-called phyto-raw-materials is a new problem spheres of energy production. The progress in phytoenergetics could considerably affect the course of prices of fossil fuels in future.
Miklúšová Viera, Bejda Ján
doaj  

In vivo anticoccidial activity of quinfamide in broilers: a preliminary report

open access: yesItalian Journal of Animal Science, 2016
The aim of this trial was to evaluate the anticoccidial efficacy of quinfamide in broilers. Three different treatments were implemented over a 49-day period as follows: quinfamide; quinfamide plus carbopol and decoquinate, all prepared as small pellets ...
Itzcoatl Aquino   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Experimental Research of Shale Pellet Swelling in Nano-Based Drilling Muds

open access: yesEnergies, 2020
The drilling of clay-rich formations, such as shale, is an extremely demanding technical and technological process. Shale consists of mixed clay minerals in different ratios and in contact with water from drilling mud.
Borivoje Pašić   +3 more
doaj   +1 more source

Product Characteristics from the Torrefaction of Bamboo Pellets in Oxidative Atmosphere [PDF]

open access: hybrid, 2021
Jacky Michael Pah   +9 more
openalex   +1 more source

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