Results 71 to 80 of about 790,408 (311)

Consumer attitudes towards the use of pellets in function of energetic efficiency [PDF]

Marketing (Beograd. 1991), 2020
Modern living conditions are characterized with concern for environmental protection and sustainable development, which implies an increase in environmental awareness of consumers and a continuous change in consumer attitudes with a goal to adopt ...
Nikolić-Ristić Dragana, Đokić Nenad
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Ultrasound-assisted extraction of itraconazole from pellets: an efficient approach for the recovery of active pharmaceutical compounds from solid dosage forms

Frontiers in Analytical Science
IntroductionItraconazole is a widely used broad-spectrum antifungal drug on a global scale. However, its poor water solubility necessitates the development of advanced formulations for its effective use.
Patricia G. Ferreira, Carolina G. S. Lima, Marcela C. de Moraes, Fernando de C. da Silva, Débora O. Futuro, Vitor F. Ferreira   +5 more
doaj   +1 more source

Comparação entre formas físicas da ração no desempenho de leitões do desmame aos setenta dias de idade Comparison between different shapes of ration in the performance of weaning pigs up to seventy days

Ciência Rural, 1995
Um estudo foi realizado no Departamento de Zootecnia da Universidade Federal de Santa Maria, com o objetivo de avaliar o efeito de três formas físicas de ração sobre o desempenho de leitões, do desmame (28 dias de idade) até 70 dias de idade.
Gerson Guarez Garcia, João Carlos Gauer da Silveira   +1 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Fourier transform infrared cell for surface studies at controlled temperatures and in controlled atmospheres with time resolution and spatial resolution [PDF]

, 1996
A new micro-Fourier transform infrared cell has been constructed and evaluated using (i) the transformation of aurichalcite crystals at 298-475 K, (ii) the adsorption/desorption of pyridine on a Cu2O/ZnO junction, and (iii) the adsorption of CO on Pt ...
Greek B. F., P. A. Sermon, V. A. Self
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A novel reactor for determination of kinetics for solid catalyzed gas reactions [PDF]

, 1994
A novel perfectly mixed laboratory reactor for determining kinetics of heterogeneously catalyzed gas-phase reactions has been developed. Perfect mixing is achieved by circulating the gas in the reactor using an axial flow impeller in a well streamlined ...
Borman, P.C., Borman, P.C., Bos, A.N.R., Bos, A.N.R., Westerterp, K.R.   +4 more
core   +2 more sources

PELLETS AND PELLETIZATION TECHNIQUES: A CRITICAL REVIEW

International Research Journal of Pharmacy, 2016
In the pharmaceutical industry , pellets can be defined a s small, free - flowing, spherical particulates manufactured by the agglomeration of fine powders or granules of drug substances and excipients using appropriate processing equipment. Pelletization has gained a great interest in recent years due to its vario us advantages over other similar ...
Ratul Deb, Abdul Baquee Ahmed
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source