Results 51 to 60 of about 55,048 (316)

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

Developmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming, Fang Liu, Hannah R. Moran, Robert L. Lalonde, Megan Adams, Nicole K. Restrepo, Parnal Joshi, Stephen C. Ekker, Karl J. Clark, Iddo Friedberg, Saulius Sumanas, Chunyue Yin, Christian Mosimann, Jeffrey J. Essner, Maura McGrail   +14 more
wiley   +1 more source

Ustekinumab trough concentration affects clinical and endoscopic outcomes in patients with refractory Crohn’s disease: a Chinese real-world study

BMC Gastroenterology, 2021
Background Ustekinumab (UST), a newly-used biologic targeting p40 subunit of IL12 and IL23 in China, exerts a confirmed therapeutic effect on the induction and maintenance therapies for refractory Crohn’s disease (CD).
Jia-yin Yao, Min Zhang, Wei Wang, Xiang Peng, Jun-zhang Zhao, Tao Liu, Zhi-wei Li, Hai-tian Sun, Pinjin Hu, Min Zhi   +9 more
doaj   +1 more source

Effect of surgical antimicrobial prophylaxis duration for colic surgery on complications and resistome

Equine Veterinary Journal, EarlyView.
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood, Alicia Long, Jairo Perez, Scott Daniel, Kyle Bittinger, Maia Aitken, Laurel Redding   +6 more
wiley   +1 more source

Exploring transvaginal sonographic characteristics of the levator ani muscle in women with postpartum pelvic floor myofascial pain

BMC Women's Health
Background Pelvic floor myofascial pain is one of the pelvic floor dysfunction diseases disturbing women after delivery. There is a lack of objective standardization for the diagnosis of pelvic floor myofascial pain due to the various symptoms and the ...
Juntong Ye, Hui Fei, Jingran Du, Yun Liu, Juan He, Mengxiong Li, Yunxia He, Pinyu Ren, Juanhua Li, Yang Xu, Jing Li, Pu Wang, Xinling Zhang, Tian Li   +13 more
doaj   +1 more source

Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasia

Frontiers in Cellular and Infection Microbiology
IntroductionEmerging evidence suggests that the vaginal microbiota is closely associated with cervical cancer. However, little is known about the relationships among the vaginal microbiota, vaginal metabolites, and cervical lesion progression in women ...
Tiantian Yu, Tiantian Yu, Shan Gao, Fen Jin, Bingbing Yan, Wendong Wang, Zhongmin Wang   +6 more
doaj   +1 more source

Validation of a handheld smartphone markerless gait‐analysis tool using an estimated groundline in horses

Equine Veterinary Journal, EarlyView.
Abstract Background A handheld smartphone‐based computer vision algorithm (RealHorse® [RH]) offers accessible alternatives for equine gait analysis but requires validation against a gold‐standard three‐dimensional multicamera optical motion capture system (Qualisys® [QS]).
Karsten Key, Jakob Kirkegaard, Katja Berg, Kristian Ringkjær Andresen, Sabrina Skov Hansen   +4 more
wiley   +1 more source

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev, Fatma Basak Tanoglu, Esma Demir Altuncu, Engin Oral   +3 more
wiley   +1 more source

Frontier knowledge and future directions of programmed cell death in clear cell renal cell carcinoma

Cell Death Discovery
Clear cell renal cell carcinoma (ccRCC) is one of the most common renal malignancies of the urinary system. Patient outcomes are relatively poor due to the lack of early diagnostic markers and resistance to existing treatment options.
Cao Fei, Xu Zhen, Zhang Shiqiang, Pang Jun   +3 more
doaj   +1 more source

Obstetrics and gynecology devices designed for low‐ and middle‐income countries: A narrative review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 71-80, April 2025.
Abstract There are many barriers contributing to poor health outcomes for women in low‐ and middle‐income countries (LMICs), one of which is the lack of necessary medical devices. Presently, the development of various kinds of devices intended to improve women's health outcomes specifically in LMICs remains underrepresented in the literature; therefore,
Dhanalakshmi Thiyagarajan, Enaam A. Adanu, K. Rivet Amico   +2 more
wiley   +1 more source

[Pelvic floor muscle training and pelvic floor disorders in women].

Gynecologie, obstetrique & fertilite, 2015
Our goal is to provide an update on the results of pelvic floor rehabilitation in the treatment of urinary incontinence and genital prolapse symptoms.Pelvic floor muscle training allows a reduction of urinary incontinence symptoms. Pelvic floor muscle contractions supervised by a healthcare professional allow cure in half cases of stress urinary ...
Thubert, Thibault, Bakker, Els, Fritel, Xavier   +2 more
openaire   +2 more sources