Results 51 to 60 of about 107,041 (362)

BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation

Cell Death and Disease, 2022
BAF53A, an important subunit of the SWI/SNF epigenetic chromatin regulatory complex, has been implicated as the driver of diverse cancers. However, the role of BAF53A in colorectal cancer (CRC) remains poorly understood.
Ziqing Yang, Dandan Huang, Manqi Meng, Wencong Wang, Junyan Feng, Lekun Fang, Honglei Chen, Shaomin Zou   +7 more
doaj   +1 more source

A randomised controlled trial of pelvic floor muscle training for stages I and II pelvic organ prolapse [PDF]

, 2009
Forty-seven women participated in a pilot study for a multi-centre randomized controlled trial of the effectiveness of pelvic floor muscle training (PFMT) for women with prolapse.
Glazener, Cathryn Margaret Anne, Hagen, Suzanne, Ramsay, Ian, Sinclair, Lesley, Stark, Diane   +4 more
core   +2 more sources

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

Advanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song, TaeHyung Kwon, Jeung Lee, Daeyoun D. Won, Brian J. Lee, Hyuk Soon Choi, Joseph C. Liao, Walter G. Park, Irene Sonu, Stephan Rogalla, Michael J. Rosen, David L. Hu, Jonathan Kuang Ziyang, Sunny Hei Wong, Bong Hyun Jun, Soh Kim, Seung‐min Park   +16 more
wiley   +1 more source

Medium- to long-term outcomes of vaginally assisted laparoscopic sacrocolpopexy in the treatment of stage III–IV pelvic organ prolapse

BMC Women's Health, 2022
Background Vaginally assisted laparoscopic sacrocolpopexy (VALS) refers to the placement of synthetic meshes through the vagina in addition to traditional laparoscopic sacrocolpopexy.
Tuo Deng, Su Wang, Xuezao Liang, Liquan Chen, Yanli Wen, Xiaowei Zhang, Lizhen Xu   +6 more
doaj   +1 more source

Low-Frequency Intravesical Electrical Stimulation for the Treatment of Acute Urinary Retention: A Promising Therapeutic Approach

Frontiers in Medicine, 2021
Acute urinary retention (AUR) is a troublesome urological disease, which causes various lower urinary tract symptoms. However, only few studies explored and evaluated the effective treatments to improve AUR. We aimed to find an effective approach to cure
Tingting Cao, Tingting Cao, Tingting Cao, Bing Xie, Bing Xie, Bing Xie, Siyuan Yang, Jiaqi Wang, Jiaqi Wang, Jiaqi Wang, Xiao Yang, Boqiang Shen, Xueke Lin, Xiuli Sun, Xiuli Sun, Xiuli Sun, Jianliu Wang, Jianliu Wang, Jianliu Wang   +18 more
doaj   +1 more source

Probiotic‐Enhanced Porous Bio‐Hybrids with Inflammatory Targeting, ROS Scavenging, and Long‐Term Drug Release for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
Probiotic‐enhanced porous bio‐hybrids (E‐xPAM@ASA), developed by coupling the drug‐loaded hairy microporous nanospheres xPAM@ASA with probiotic EcN, integrate inflammatory‐targeting, ROS scavenging, and long‐term release of 5‐ASA to improve inflammation and regulate microbiota structure in the DSS‐induced colitis model, providing an advanced strategy ...
Luna Quan, Yang Ouyang, Weiwen Liang, Zixin Chen, Dongtian Miao, Bingna Zheng, Dingcai Wu, Rongkang Huang   +7 more
wiley   +1 more source

Ustekinumab trough concentration affects clinical and endoscopic outcomes in patients with refractory Crohn’s disease: a Chinese real-world study

BMC Gastroenterology, 2021
Background Ustekinumab (UST), a newly-used biologic targeting p40 subunit of IL12 and IL23 in China, exerts a confirmed therapeutic effect on the induction and maintenance therapies for refractory Crohn’s disease (CD).
Jia-yin Yao, Min Zhang, Wei Wang, Xiang Peng, Jun-zhang Zhao, Tao Liu, Zhi-wei Li, Hai-tian Sun, Pinjin Hu, Min Zhi   +9 more
doaj   +1 more source

Pelvic Organ Prolapse-Associated Cystitis [PDF]

, 2014
This thesis concerns the construction of 2,3-dihydro-4r7-pyran-4-one and 3(2//)-furanone ring systems by mercury(II)-catalysed reactions, or by more conventional cyclisations, and the potential of such reactions for the synthesis of natural products ...
Hamid, R, Losco, G
core   +1 more source

Integrated total pelvic floor ultrasound in pelvic floor dysfunction

Continence, 2023
Integrated total pelvic floor ultrasound is a combination of endoanal, transperineal, and endovaginal ultrasound used for the static and dynamic assessment of the entire pelvic floor. It can be used as a screening investigation for defaecatory dysfunction so that defaecatory radiological imaging may be avoided.
A.J. Hainsworth, T. Gala, L. Johnston, D. Solanki, L. Ferrari, A.M.P. Schizas, G. Santoro   +6 more
openaire   +2 more sources

Surgical Procedure of Lateral Lymph Node Dissection for Advanced Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Lateral lymph node dissection (LLND) is an effective surgical approach for lower rectal cancer. This paper outlines key points from the Japan Society of Gastroenterological Surgery consensus meeting, including standardized LLND techniques and procedural highlights.
Mamoru Uemura, Jun Watanabe, Akio Shiomi, Takashi Akiyoshi, George J. Chang, Yukihide Kanemitsu, Ichiro Takemasa, Yoshiharu Sakai, Masahiko Watanabe, Itaru Endo   +9 more
wiley   +1 more source