Results 71 to 80 of about 58,121 (330)

Dolichocolon is common in pediatric gastroenterology patients with constipation and associated complaints

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Dolichocolon (DC), classified under ICD‐10 code Q43.8 (“Other specified congenital malformations of intestine”), refers to an elongated or redundant large intestine. Recent studies in adults indicate a role for dolichocolon in constipation and disorders of gut‐brain interaction.
David Simon, Donovan Berens, Raul Zambrana Valenzuela, Arvind Mohan, Partha Chakraborty, Timot Kellermayer, Eric H. Chiou, Craig L. Jensen, Ricardo A. Arbizu, Marla B. K. Sammer, Richard Kellermayer   +10 more
wiley   +1 more source

Associations of cigarette use, e-cigarette use, and dual use, with nocturia and urge urinary incontinence in US adults

Tobacco Induced Diseases
Introduction Associations of cigarette use, e-cigarette use, and dual use, with nocturia and urge urinary incontinence (UUI) remain unclear. We performed this study to investigate the associations of cigarette use, e-cigarette use, and dual use, with ...
Xiangwei Yang, Yuhang Xie, Hong Chen, Junfu Zhang, Wenhan Qiu, Jun Pang   +5 more
doaj   +1 more source

When manual disimpaction isn't enough: Case report and review of neostigmine's role in refractory constipation management

JPGN Reports, EarlyView.
ABSTRACT Severe refractory constipation can lead to fecal retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo‐obstruction but rarely for refractory constipation. Here, we report a 21‐year‐old male with chronic
Mojdeh Mostafavi, Sarah Lee, Victoria Martin   +2 more
wiley   +1 more source

Novel mRNA adjuvant ImmunER enhances prostate cancer tumor-associated antigen mRNA therapy via augmenting T cell activity

OncoImmunology
Prostate cancer (PCa) is characterized as a “cold tumor” with limited immune responses, rendering the tumor resistant to immune checkpoint inhibitors (ICI).
Zhen Xu, Ze-Xiu Xiao, Jing Wang, Hao-Wei Qiu, Fei Cao, Shi-Qiang Zhang, Yuan-Dong Xu, Han-Qi Lei, Heng Xia, Yun-Ru He, Gao-Feng Zha, Jun Pang   +11 more
doaj   +1 more source

A Novel Semi‐Quantified Method for Grading Sonographic Severity of Adenomyosis and its Relation With Clinical Symptoms

Journal of Ultrasound in Medicine, EarlyView.
Objective To correlate the sonographic severity of adenomyosis, assessed with real‐time ultrasound and a novel semi‐quantified method (XI‐VOCAL counting and categories) with adenomyosis‐associated symptoms. Methods This observational study was conducted in a tertiary referral outpatient clinic.
Lisa M. Trommelen, Cilla Verbeek, Thierry van den Bosch, Karin P. M. van Galen, Judith A. F. Huirne, Robert A. de Leeuw   +5 more
wiley   +1 more source

Detrusor Overactivity and Urodynamics

Neurourology and Urodynamics, EarlyView.
ABSTRACT While overactive bladder (OAB) is a clinical diagnosis, detrusor overactivity is identified through urodynamic testing. UDS is usually considered when primary treatment for OAB fails, because UDS is expensive, time consuming, invasive, and sometimes inaccurate, and it is not considered to influence treatment strategy substantially.
Laura N. Nguyen, Geneviève Nadeau
wiley   +1 more source

Enhancing the potency of 5T4 mRNA vaccine by CD70 mRNA-LNPs through ADCC and T cell boosting in prostate cancer therapy

Journal of Nanobiotechnology
Background Prostate cancer remains a significant health challenge, as conventional treatments often fail to provide long-term benefits in the advanced stages.
Fei Cao, Yuandong Xu, Yupeng Guan, Kexin Zhang, Haowei Qiu, Zhen Xu, Yunru He, Ze Xiu Xiao, Gao-feng Zha, Jun Pang   +9 more
doaj   +1 more source

Association of Knowledge and Presence of Pelvic Floor Disorders and Participation in Pelvic Floor Exercises: A Cross-sectional Study.

Female Pelvic Medicine & Reconstructive Surgery, 2020
INTRODUCTION Women's baseline knowledge of pelvic floor exercises (PFEs) and pelvic floor disorders (PFDs) is not well established, as is their knowledge regarding PFE and participation in such exercise.
S. Goodridge, Leah P Chisholm, J. Heft, S. Hartigan, M. Kaufman, R. Dmochowski, T. Stewart, W. Reynolds   +7 more
semanticscholar   +1 more source

Should We Consider Sacral Nerve Stimulation as a Treatment for Neurogenic Lower Urinary Tract Dysfunction? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To explore the boundary of clinical use of sacral nerve stimulation (SNS) in neurogenic lower urinary tract dysfunction (NLUTD), identifying barriers to approval and early‐impact research questions. Methods This review is derived from a proposal discussion at the International Consultation on Incontinence‐Research Society in Bristol in ...
Marcus J. Drake, Mathijs de Rijk, Stefania Musco, Jalesh Panicker, Michał Późniak, Nikita Bhatt, Brigitte Schurch   +6 more
wiley   +1 more source

Association of cigarette use with risk of prostate cancer among US males: a cross-sectional study from NHANES 1999–2020

BMC Public Health
Background Association of cigarette use with risk of prostate cancer remains unclear. We performed this study to examine whether cigarette use is associated with increased risk of prostate cancer.
Xiangwei Yang, Hong Chen, Junfu Zhang, Shiqiang Zhang, Yongda Socrates Wu, Jun Pang   +5 more
doaj   +1 more source