Targeting YAP1-CD70 axis potentiates the efficacy of anti-PD-1 therapy in prostate cancer
The mechanisms by which prostate cancer (PCa) evades anti-tumor immunity and the immune checkpoint blockade (ICB) response are poorly understood. Yes-associated protein 1 (YAP1) activation is a common feature in PCa.
Tongyu Tong +11 more
doaj +1 more source
Dynamic magnetic resonance imaging of the female pelvic floor—a pictorial review
Pelvic floor dysfunctions represent a range of functional disorders that frequently occur in adult women, carrying a significant burden on the quality of life, and its incidence tends to increase attending to the expected aging of the population.
João Cunha Salvador +3 more
doaj +1 more source
The mechanism of labor in nonhuman primates: A look inside
Abstract While in humans, the flexed position of the fetus and its rotating course down the birth canal are well documented, in other primates the mechanism of labor is unknown. Despite the lack of comparative data, it is commonly assumed that the human obstetric mechanism is unique, and anthropologists have disputed when and why the transition to the ...
Melissa K. Stoller
wiley +1 more source
Frequency of pelvic floor disorders and related socio-demographic and obstetric determinants in reproductive aged women in Tabriz city, 2021-2022 [PDF]
Introduction: Pelvic floor disorders are one of the most common morbidities in women, which have negative consequences on women's daily life. Since the total prevalence of this disorder among Iranian′s women has not been reported by appropriate tools ...
Fatemeh Rashidi, Mojgan Mirghafourvand
doaj +1 more source
Abstract Maternal and neonatal morbidity and mortality have declined dramatically during the last century. Historical data are therefore important sources to study the evolutionary selection pressures related to childbirth and how they have fluctuated over time.
Mirella Woodert +7 more
wiley +1 more source
Comprehensive evaluation of pelvic floor disorders [PDF]
Pelvic floor disorders are an underdiagnosed source of morbidity and decreased quality of life for women while it is a much less common disorder in men.
Md Nor, Azmi
core
Predicting risk of pelvic floor disorders 12 and 20 years after delivery. [PDF]
Little progress has been made in the prevention of pelvic floor disorders, despite their significant health and economic impact. The identification of women who are at risk remains a key element in targeting prevention and planning health resource ...
MacArthur, Christine +10 more
core +4 more sources
Creation and Implementation of Virtual Urogynecology Patient Cases for Medical Student Education
Introduction Urogynecologic disorders are highly prevalent, and many physicians across various specialties will encounter and care for patients with pelvic floor disorders.
Jacqueline Y. Kikuchi +10 more
doaj +1 more source
Human evolution and the obstetrical dilemma: The pelvic floor hypothesis
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley +1 more source
The Pelvic Floor Function Disorders and Quality of Life [PDF]
Pelvic floor disorders affect millions of women throughout the world. The prevalence of pelvic floor disorders increas with age, pelvic floor disorders affect women, their families and caregivers and society.
BİLGİÇ, DİLEK +1 more
core

