Results 61 to 70 of about 101,201 (311)

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Surgical treatment of primary malignant tumors of the sacrum [PDF]

, 2014
Objectives The objective of the authors was to provide an up-to-date review about the epidemiology, diagnosis and surgical management of the malignant primary sacral tumors.
Lazáry, Áron, Szövérfi, Zsolt, Varga, Péter Pál   +2 more
core   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Metachronous occurrence of two different histological subtypes of endometriosis-related neoplasms

Gynecologic Oncology Reports, 2019
A solitary pelvic tumor after treating a primary endometriosis-related neoplasm is usually considered a recurrence but may actually be a primary endometriosis-related peritoneal neoplasm.
Takashi Uehara, Hiroshi Yoshida, Keisei Tate, Tomoyasu Kato   +3 more
doaj   +1 more source

Struma Ovarii Associated with Pseudo- Meigs’Syndrome [PDF]

, 2012
Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs’ syndrome) in 5% of cases.
Gangane, NM, Gulhane, SR, Sinha, RT
core   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

Sacroiliitis as a mask of neoplasms in childhood: analysis of a clinical case series

Современная ревматология, 2019
The paper presents a clinical case series that includes 12 children with pelvic bone neoplasms mimicking sacroiliitis, which led to the initial misdiagnosis of enthesitis-related arthritis.
M. M. Karabakhtsyan, N. T. Garipova, L. S. Sorokina, E. A. Isupova, I. A. Chikova, A. S. Maletin, M. M. Kostik, A. Yu. Mushkin   +7 more
doaj   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Successful outpatient management of pelvic actinomycosis by ceftriaxone: a report of three cases

Brazilian Journal of Infectious Diseases
Pelvic actinomycosis is a chronic granulomatous suppurative disease caused by actinomyces israeli. Intravenous penicillin is the preferred antimicrobial but it requires hospitalization up to one month.
Eda Demir Onal, Akif Altinbas, Ibrahim Koral Onal, Sibel Ascioglu, Meltem Gulsun Akpinar, Cigdem Himmetoglu, Yesim Cetinkaya Sardan   +6 more
doaj   +1 more source

Pelvic actinomycosis presenting with a large abscess and bowel stenosis with marked response to conservative treatment: a case report

Journal of Medical Case Reports, 2007
Pelvic actinomycosis is a rare disease that can result in abscess formation, bowel obstruction, and other serious complications. Moreover, the correct diagnosis can seldom be established before radical surgery because the disease often mimics pelvic ...
Nozawa Hiroaki, Yamada Yoshinao, Muto Yasuhiko, Arita Shirane, Aisaka Kohzo   +4 more
doaj   +1 more source