Results 51 to 60 of about 119,526 (169)

Pemphigus foliaceus transforming to pemphigus vulgaris: a case report

Frontiers in Medicine
Pemphigus represents a family of acantholytic autoimmune vesiculobullous diseases. It is classified into multiple subtypes, the two most common of which are pemphigus vulgaris and pemphigus foliaceus. The transition between these two subtypes is uncommon.
Mandlin Abdulaziz Almousa, Mandlin Abdulaziz Almousa, Mandlin Abdulaziz Almousa, Mandlin Abdulaziz Almousa, Navya Kuchibhotla, Navya Kuchibhotla, Navya Kuchibhotla, Lama Alabdulaaly, Lama Alabdulaaly, Lama Alabdulaaly, Lama Alabdulaaly, Marcus Couey, Vikki Noonan, Herve Sroussi, Herve Sroussi, Herve Sroussi   +15 more
doaj   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond, Victoria Soto, Beatriz Abdo Abujamra, Franco Rongioletti, John A. McGrath, Ivan Jozic, Paolo Romanelli   +6 more
wiley   +1 more source

Lichenoid and Granulomatous Stomatitis: Three Additional Cases and Detailed Immunohistochemical Analysis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Lichenoid and granulomatous stomatitis (LGS) is a rare condition, with clinicopathological features resembling lichenoid and granulomatous dermatitis. Despite increasing reports, its etiology remains unclear and detailed immunohistochemical (IHC) studies are lacking.
Mariana Paravani Palaçon, Karina Kendelhy Santos, Karina Helen Martins, Cecília Aparecida de Oliveira Campos, Ana Terezinha Marques Mesquita, Evânio Vilela Silva, Thales Peres Candido Moreira, Gabriel Enrique Tantalean Laor, Victor Hugo Toral‐Rizo, Alan Grupioni Lourenço, Heitor Albergoni Silveira, Jorge Esquiche León, Andreia Bufalino   +12 more
wiley   +1 more source

Pemphigus vulgaris

, 2008
Pemphigus vulgaris is the most common form of Pemphigus, is an autoimmune disease of the skin and mucous membrane characterized by impaired cell adhesion within the epidermis leading to the formation of intraepidermal bullae.
Radhika, Vijeev Vasudevan, Vadi V Bharathan, null Radhika, VadiV Bharathan   +4 more
core   +1 more source

Incidência do pênfigo vulgar ultrapassa a do pênfigo foliáceo em região endêmica para pênfigo foliáceo: análise de série histórica de 21 anos Incidence of pemphigus vulgaris exceeds that of pemphigus foliaceus in a region where pemphigus foliaceus is endemic: analysis of a 21-year historical series

Anais Brasileiros de Dermatologia, 2011
FUNDAMENTO: Há dois tipos principais de pênfigo: pênfigo vulgar e pênfigo foliáceo. Nos últimos anos, mudanças clínicas e epidemiológicas relacionadas aos pênfigos têm sido observadas.
Gilson Antonio Pereira Gonçalves, Moema Mignac Cumming Brito, Adriana Martinelli Salathiel, Thais Serraino Ferraz, Domingos Alves, Ana Maria Ferreira Roselino   +5 more
doaj   +1 more source

Cyclophosphamide is associated with long‐term treatment‐free remission in patients with pemphigus

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objective Pemphigus treatment has seen significant advancements, yet long‐term remission remains a challenge. Comparative data on the long‐term effectiveness of available therapies are limited. We compared 10‐year relapse rates in pemphigus patients treated with azathioprine or cyclophosphamide plus high‐dose IV corticosteroids ...
Bettina Santler, Simon Lüdtke, Lena Dietze, Marie Schiffmann, Dominik Straube, Jan Ehrchen   +5 more
wiley   +1 more source

Oral Pemphigus Vulgaris: Case Report [PDF]

, 2015
BACKGROUND: Pemphigus is a potentially life threatening autoimmune disease that causes blisters and erosions of the skin and the mucous membrane. The epithelial lesions are a result of auto-antibodies that react with desmosomal glycoproteins that are ...
Malhotra, V, Arora, M, Rai, A, Naikmasur, V, Sattur, A   +4 more
core   +1 more source

Data on HLA class I/II profile in Brazilian pemphigus patients

Data in Brief, 2016
Pemphigus are blistering autoimmune diseases related with genetic and environmental factors. Here we describe HLA genotyping in pemphigus patients. First, we review the HLA class I/II data on pemphigus reported in Brazilian samples and then present the ...
Maria José Franco Brochado, Daniela Francisca Nascimento, Neifi Hassan Saloum Deghaide, Eduardo Antonio Donadi, Ana Maria Roselino   +4 more
doaj   +1 more source

Reassessing Remission in Pemphigus Vulgaris: Beyond Complete Remission Towards Meaningful Disease Control

International Journal of Dermatology, EarlyView.
ABSTRACT Current remission criteria for pemphigus vulgaris rely on binary, lesion‐based endpoints that do not capture immunological status, treatment toxicity, or patient quality of life. We argue for a multidimensional framework incorporating minimal disease activity, validated severity scores, glucocorticoid toxicity indices, and patient‐reported ...
Rhea Ahuja, Sumin Hong, Dédée F. Murrell   +2 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source