Results 31 to 40 of about 7,473 (181)

Dipeptidyl Peptidase‐4 Inhibitor Use and Risk of Pemphigus Vulgaris and Foliaceus: A Retrospective Cohort Study Using Databases of the Korea National Health Insurance Claims and the National Health Screening Examination

The Journal of Dermatology, EarlyView.
ABSTRACT Although population‐based studies have reported an increased risk of bullous pemphigoid and pemphigus associated with dipeptidyl peptidase‐4 (DPP‐4) inhibitors, there is limited, well‐designed epidemiological evidence for pemphigus vulgaris (PV), which has only been supported by case reports thus far.
Jaein Lee, Jae Hyun Bae, Seokyung Hahn
wiley   +1 more source

Involvement of Nail Apparatus in Pemphigus Vulgaris in Ethnic Poles Is Infrequent

Frontiers in Medicine, 2018
Pemphigus vulgaris lesions have a tendency to localize around natural body orifices. The aim here was to analyze the involvement of nail apparatus in pemphigus vulgaris.
Pawel Pietkiewicz, Pawel Pietkiewicz, Monika Bowszyc-Dmochowska, Justyna Gornowicz-Porowska, Marian Dmochowski   +4 more
doaj   +1 more source

Consensus on the treatment of autoimmune bullous dermatoses: pemphigus vulgaris and pemphigus foliaceus - Brazilian Society of Dermatology [PDF]

Anais Brasileiros de Dermatologia, 2019
: Pemphigus are intraepidermal autoimmune bullous dermatoses that occur with lesions on the skin and / or mucous membranes. The most frequent types are pemphigus vulgaris and pemphigus foliaceus (classic and endemic).
Adriana Maria Porro, Günter Hans Filho, Claudia Giuli Santi   +2 more
doaj   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond, Victoria Soto, Beatriz Abdo Abujamra, Franco Rongioletti, John A. McGrath, Ivan Jozic, Paolo Romanelli   +6 more
wiley   +1 more source

Pemphigus vegetans with isolated involvement of the nose and chest: rare variant of pemphigus vulgaris [PDF]

Anais Brasileiros de Dermatologia, 2019
: Pemphigus vulgaris is chronic bullous disease that manifests as bullae and erosions of skin and mucosas, with intraepidermal suprabasal cleft formation seen in the histological examination.
Raisa Ilena Caranhas Feitoza, Mônica Santos, Maria da Conceição Almeida Schettini, Silvana de Albuquerque Damasceno Ferreira   +3 more
doaj   +2 more sources

Lichenoid and Granulomatous Stomatitis: Three Additional Cases and Detailed Immunohistochemical Analysis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Lichenoid and granulomatous stomatitis (LGS) is a rare condition, with clinicopathological features resembling lichenoid and granulomatous dermatitis. Despite increasing reports, its etiology remains unclear and detailed immunohistochemical (IHC) studies are lacking.
Mariana Paravani Palaçon, Karina Kendelhy Santos, Karina Helen Martins, Cecília Aparecida de Oliveira Campos, Ana Terezinha Marques Mesquita, Evânio Vilela Silva, Thales Peres Candido Moreira, Gabriel Enrique Tantalean Laor, Victor Hugo Toral‐Rizo, Alan Grupioni Lourenço, Heitor Albergoni Silveira, Jorge Esquiche León, Andreia Bufalino   +12 more
wiley   +1 more source

A case report on generalized pemphigus vulgaris treated with rituximaba

Journal of Ideas in Health, 2023
Background: Pemphigus vulgaris has an obscure etiology; the presence of autoantibodies is coherent with an autoimmune disease. Rituximab a monoclonal antibody that specifically targets the CD20 antigen of B lymphocytes, has arisen as a novel treatment ...
Sakhiya Jagdish , Dhruv Jagdish Sakhiya , Jashmine Mukeshbhai Gandhi, Feral Ravi Daruwala   +3 more
doaj   +1 more source

Cyclophosphamide is associated with long‐term treatment‐free remission in patients with pemphigus

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objective Pemphigus treatment has seen significant advancements, yet long‐term remission remains a challenge. Comparative data on the long‐term effectiveness of available therapies are limited. We compared 10‐year relapse rates in pemphigus patients treated with azathioprine or cyclophosphamide plus high‐dose IV corticosteroids ...
Bettina Santler, Simon Lüdtke, Lena Dietze, Marie Schiffmann, Dominik Straube, Jan Ehrchen   +5 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source