Results 111 to 120 of about 1,626,184 (305)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Online No Child Left Behind Survey Responses from Alabama vs. the National Average [PDF]

open access: yes, 2005
The PEN national office launched a 2005 No Child Left Behind (NCLB) online survey to follow up on the 2004 survey. The 2004 survey generated 12,000 responses and greatly influenced the recommendations in the "Open to the Public" report released in March ...

core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

′PEN′ appendicitis

open access: yesJournal of Indian Association of Pediatric Surgeons, 2010
We report a three-year-old boy who ingested the tip of a pen and presented with signs of appendicitis. Plain abdominal radiographs showed the foreign body in the right iliac fossa. Surgical exploration revealed perforated appendix and the foreign body in
Amadou Issa   +3 more
doaj  

Method of tracing contour patterns for use in making gradual contour resin matrix composites [PDF]

open access: yes, 1983
The invention relates to methods for making alminate patterns for a resin matrix composite structural component. A sheet of paper is temporarily adhered to a model of the structrual component.
Fontes, M. J.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Universal Tool Interaction Force Estimation Approach for Robotic Tool Manipulation

open access: yesSensors
The six-degree-of-freedom (6-DoF) interaction forces/torque of the tool-end play an important role in the robotic tool manipulation using a gripper, which are usually indirectly measured by a robot wrist force/torque sensor.
Diyun Wen   +5 more
doaj   +1 more source

Online No Child Left Behind Survey Responses from South Carolina vs. the National Average [PDF]

open access: yes, 2005
The PEN national office launched a 2005 No Child Left Behind (NCLB) online survey to follow up on the 2004 survey. The 2004 survey generated 12,000 responses and greatly influenced the recommendations in the "Open to the Public" report released in March ...

core  

Your Soul for a Pen?

open access: yesJournal of the American College of Cardiology, 2007
![Figure][1] I recently had the privilege of serving as the Samuel and Edith Marcus Visiting Professor Lecturer at the University of Arizona. During the 2-day visit Frank Marcus, the loving son of the honorees and my host, shared with me his feelings regarding the need for greater ...
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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