Results 101 to 110 of about 2,636 (206)

Control of Sequences and H‐Bonding Motifs in IEM‐Derived Copolymers Enables Mechanical Tunability, Self‐Healing, and Clusterization‐Triggered Emission

open access: yesAngewandte Chemie, EarlyView.
In IEM‐derived gradient copolymers, the structure of H‐bonding motifs and chain sequence distribution jointly govern mechanical performance, self‐healing, and clusterization‐triggered emission (CTE) behavior. Quadruple H‐bonding motifs in a gradient architecture promote nanoscale clustering that simultaneously tunes modulus across two orders of ...
Hanshu Wu   +6 more
wiley   +2 more sources

Chemoenzymatic Synthesis of 6‐Sulfo Sialyl Lewisx Containing Glycans to Probe the Receptor Specificity of MERS Coronavirus

open access: yesAngewandte Chemie, EarlyView.
A chemoenzymatic methodology is described that provided a panel of 6‐sulfo sialyl Lewisx‐containing glycans that were probed for receptor specificity of MERS‐CoV. Although the fucoside of 6‐sulfo‐SLex does not directly interact with the spike, it pre‐organizes the molecule into a conformation to allow a salt bridge between the sulfate and the ...
Yunfei Wu   +7 more
wiley   +2 more sources

Redox‐Modulated σ‐Bond Reactivity in a Radical‐Anion Dimer

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.
A radialene‐based radical anion σ‐dimer comprising an elongated C‐C bond exhibits orthogonal stimuli responsiveness. Homolytic cleavage of the dimer to the radical state is triggered by mechanical strain and high temperature. Dimer scission is also achieved via oxidation, resulting in formation of neutral radialenes.
Sushil Ranjan Bhatta   +8 more
wiley   +1 more source

Dynamic helical poly[4]helicene nanoribbon. [PDF]

open access: yesNat Commun
Ikai T   +6 more
europepmc   +1 more source

Polymeric Polyaldehyde Approach to Develop Robust Dynamic Covalent Adaptive Polyimine Networks. [PDF]

open access: yesMacromol Rapid Commun
Dolui S   +8 more
europepmc   +1 more source

Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity

open access: yesAngewandte Chemie International Edition, EarlyView.
To make exceptionally effective drugs, thinking “outside the binding site” is required. This work reveals that counterintuitive targeting of a kinase‐conserved region can lead to highly selective binding. Inhibitor discovery coupled to x‐ray crystallography shows that a network of noncanonical interactions and long‐range effects of distant unique amino
Nico J. Seidler   +20 more
wiley   +1 more source

Chiral Memory-Driven Helical Supramolecular Photodetector for Deciphering Circularly Polarized Light. [PDF]

open access: yesAdv Mater
Gao K   +15 more
europepmc   +1 more source

Modeling identities among the first-sedentary communities: Emergence of clay personal ornaments in Epipaleolithic Southwest Asia. [PDF]

open access: yesSci Adv
Davin L   +9 more
europepmc   +1 more source

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