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One long-standing approach for improving transdermal drug delivery uses penetration enhancers (also called sorption promoters or accelerants) which penetrate into skin to reversibly decrease the barrier resistance. Numerous compounds have been evaluated for penetration enhancing activity, including sulphoxides (such as dimethylsulphoxide, DMSO), Azones
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The cosmetic industry continues to expand worldwide. The claims described on a cosmetic product label or in promotional material must be substantiated with scientific data or clinical studies, ensuring that the product actually has the promised effect. Cosmetics must be safe to use over a long term, so safety assurance is critical.
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