Results 51 to 60 of about 486,358 (266)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Drug delivery system based on dendritic nanoparticles for enhancement of intravesical instillation
International Journal of Nanomedicine, 2017 Xuefeng Qiu,1,2,* Kai Cao,1,2,* Tingsheng Lin,1,2 Wei Chen,1 Ahu Yuan,2 Jinhui Wu,2 Yiqiao Hu,2 Hongqian Guo1 1Department of Urology, Drum Tower Hospital, Medical School of Nanjing University, Institute of Urology, Nanjing University, Nanjing, China ...
Qiu X +7 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Use of hydromonitor roller bits for drilling blast boreholes
Известия высших учебных заведений: Геология и разведкаBackground. Blast boreholes can be drilled using various drilling tools. The drilling efficiency of roller bits (up to 30 m per shift in Azerbaijan) is significantly higher than that of other drilling tools (10—15 m per shift), which explains their wider
R. S. Ibrahimov +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Preliminary Study for Designing a Novel Vein-Visualizing Device
Sensors, 2017 Venipuncture is an important health diagnosis process. Although venipuncture is one of the most commonly performed procedures in medical environments, locating the veins of infants, obese, anemic, or colored patients is still an arduous task even for ...
Donghoon Kim +3 more
doaj +1 more source
Case report: Ultrasound diagnosis of fish bone penetration into the thyroid
Clinical Case Reports, 2020 Key Clinical Message Ultrasonography is useful in the diagnosis of foreign body migrations (eg, fish bones) into the soft tissues of the neck.
Gaëtan Cavelier +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Assessment of the Boron Treatability Level of Lesser-Known Timber Species by the Impregnation Method
Лесной журналFaced with the escalating crisis of global deforestation, including particularly alarming rates in Sri Lanka, researchers have turned their attention to the potential of boronbased preservatives for treating timber. The comprehensive study of the samples
Vindhya Bandara +4 more
doaj +1 more source
Penetrating Orbitocranial Injury
Acta Clinica Croatica, 2018 - A case of a 37-year-old female patient is presented. The patient was admitted to the Surgical Emergency Unit after accidental fall on a metal rod when she had sustained stab injury of the right orbit with penetration into the right frontal brain lobe.
Marisa Klančnik +7 more
openaire +4 more sources