Results 81 to 90 of about 802,819 (312)

Penetration of Chlorhexidine into Human Skin [PDF]

, 2008
This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate.
Karpanen, T. J., Conway, Barbara R, Karpanen, Tarja J., Worthington, Tony, Hilton, Anthony C., Elliott, Tom S.J., Worthington, T., Elliott, T. S. J., Lambert, Peter A., Conway, Barbara R., Lambert, P. A., Hilton, A. C.   +11 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Mutagenic Analysis of a DNA Translocating Tube’s Interior Surface

Viruses, 2020
Bacteriophage ϕX174 uses a decamer of DNA piloting proteins to penetrate its host. These proteins oligomerize into a cell wall-spanning tube, wide enough for genome passage.
Aaron P. Roznowski, Julia M. Fisher, Bentley A. Fane   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Penetrating Orbitocranial Injury

Acta Clinica Croatica, 2018
- A case of a 37-year-old female patient is presented. The patient was admitted to the Surgical Emergency Unit after accidental fall on a metal rod when she had sustained stab injury of the right orbit with penetration into the right frontal brain lobe.
Marisa Klančnik, Petar Ivanišević, Slaven Lupi-Ferandin, Ante Sučić, Vlatko Ledenko, Mladen Lešin, Marina Krnić Martinić, Ljubica Kuščić-Juretić   +7 more
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effects of PEV Penetration on Voltage Unbalance

, 2014
Balancing loads in low voltage networks is a challenging task due to a continuous fluctuation in the power demand. Voltage unbalance is a condition in which the voltage phasors differ in amplitude and/or do not have its normal 120° phase relationship ...
Ahmed M. A. Haidar, Kashem M. Muttaqi, Muttaqi, Kashem M., Haidar, Ahmed M. A.   +3 more
core   +1 more source

Stealth Aircraft Penetration Trajectory Planning in 3D Complex Dynamic Environment Based on Sparse A* Algorithm

Aerospace
To find a trajectory with low radar detection probability for stealth aircraft under the assumption of 2D space, performing a rapid turning maneuver is a useful way to reduce the radar detection probability of an aircraft by changing the azimuth angle ...
Jingxin Guan, Jun Huang, Lei Song, Xiaoqiang Lu   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source