Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Effect of nano-size calcium carbonate on perforation resistance of medium- density polyethylene
Journal of Advanced Materials in Engineering, 2011 In this article, the role of nano-size calcium carbonate in penetration resistance of medium- density polyethylene (PE) was investigated through experiments.
F. Hosseinabadi +4 more
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Soil resistance to penetration in cotton rows and interrows
, 2017 The soil physical quality is one of the most determinant factors for the development of any crop. This study aimed to assess the sample representativeness in soil resistance to penetration mappings taken in rows and interrows of the cotton crop, under ...
Cassiano G. Roque (10383844) +3 more
core +1 more source
The effect of microsilica on the setting time of high-strength concrete [PDF]
Fanāvarī-i āmūzish, 2006 This paper is the result of laboratory work performed on the initial and final setting times of high-strength concrete with different percentages of microsilica.
M. Mazloom
doaj
A semi-empirical formula based on a modified general penetration resistance for predicting the motion of the rigid projectile. [PDF]
Heliyon, 2023 Zhang Z, Wu Y, Huang F.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Wheat Susceptibility Genes TaCAMTA2 and TaCAMTA3 Negatively Regulate Post-Penetration Resistance against Blumeria graminis forma specialis tritici. [PDF]
Int J Mol Sci, 2023 Li M, Yang Z, Liu J, Chang C.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Effect of Manufactured Sand with Different Quality on Chloride Penetration Resistance of High-Strength Recycled Concrete. [PDF]
Materials (Basel), 2021 Feng J, Dong C, Chen C, Wang X, Qian Z.
europepmc +1 more source