Results 61 to 70 of about 2,456,171 (205)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Sobrecompactación del suelo agricola parte I: influencia diferencial del peso y del número de pasadas Overcompaction of agricultural soil part I: differential influence of axle load and number of passes

Revista Brasileira de Engenharia Agrícola e Ambiental, 2000
Han sido objetivos principales de este trabajo, tanto el discriminar la responsabilidad de las variables independientes, peso y número de pasadas, en la distribución vertical de la compactación inducida, como obtener evidencia que permita decidir la ...
Daniel Jorajuria, Laura Draghi
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Influence of low gravity on the penetration resistance of lunar regolith

npj Microgravity
Lunar surface operations conducted by the United States and the Soviet Union confirmed that penetration resistance is a key indicator for evaluating the engineering properties of lunar regolith.
Jun Chen, Ruilin Li, Shigen Fu
doaj   +1 more source

Compactación inducida por el tránsito vehicular sobre un suelo en producción hortícola Induced compaction by the vehicular traffic in a soil for horticultural crop production

Revista Brasileira de Engenharia Agrícola e Ambiental, 2000
Se realizaron ensayos en campo con el objeto de caracterizar el estado de compactación de un suelo en producción hortícola inducida por el tránsito, luego del desarrollo del ciclo de un cultivo de repollo (Brassica oleracea L.
Antonino Marcelo Terminiello, Roberto Hernan Balbuena, Jorge Alejandro Claverie, Juan Pablo Casado   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Penetration of a glass-faced transparent elastomeric resin by a lead-antimony-cored bullet [PDF]

, 2008
The penetration of the lead antimony-cored 7.62 mm × 51 mm bullet into a glass- faced polyurethane elastomeric polymer resin has been studied. The resulting craters in the resin contained elongated bullet core material that had a significant amount of ...
Hazell, P.J., Edwards, Michael R., Hazell, Paul J., Edwards, M.R., Erskine, J., Longstaff, H.   +5 more
core   +1 more source

Analysis of Penetration Performance Between a Hollow Penetrator and Seabed Clay by Coupled Eulerian–Lagrangian Method

Applied Sciences
Penetrating and coring technology is a critical approach for acquiring undisturbed long-columnar seabed sediment samples. The configuration and parameters of the penetrator structure directly affect penetration performance during the penetration process,
Jieneng Liang, Zhiwen Zhen, Heying Hou, Jian Zhang   +3 more
doaj   +1 more source

Physical attributes of Cambisol in apple (Malus domestica Borkh. cv. Gala) orchard under different weed management systems in Urubici, Plan alto Serrano SC, Brasil

Acta Agronómica, 2017
The aim of this research was to evaluate the physical attributes of Cambisol in apple (Malus domestica Borkh. cv. Gala) orchard under different weed management systems in the state of Santa Catarina (SC), Brazil.
Daniela Schmitz, Arcangelo Loss, Bruno Salvador Oliveira, Paulo Emilio Lovato, Milton da Veiga, Gustavo Brunetto, Pierre Curmi, Jucinei José Comin   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source