Spatial variations in yield occur in all agricultural fields to some degree. Knowledge of the reasons for these variations, especially temporally stable yield patterns, is needed in order to improve productivity by changing production methods or inputs ...
Elisabeth Bölenius +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Delayed compression and breakage of crushed mudstones due to the drying/wetting and temperature cycles [PDF]
Soft sedimentary rocks, especially mudstones, disintegrated or crumbled when subjected to cyclic drying and wetting, known as slaking, which was the cause of severe slope failures and ground settlement.
Nihaaj Mohamed +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
EVALUATION OF VARIOUS SOIL PARAMETERS OF Al-EMARA CITY FROM FIELD AND LABORATORY TESTS
This paper describes the geotechnical characteristic of soil located at Al-Emara city southern Iraq. The paper presents the data advanced from the field investigations performed at many projects at Al-Emara city.
Mudhafar K. Hameedi
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Penetration of Chlorhexidine into Human Skin [PDF]
This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate.
Karpanen, T. J. +11 more
core +1 more source
IMPACT OF THE REPEATED TRACTOR PASSES ON SOME PHYSICAL PROPERTIES OF SILTY LOAM SOIL [PDF]
The aim of this paper was to quantify soil compaction induced by tractor traffic on untilled wet silty loam soil (Mollic Fluvisol). Changes in penetration resistance, bulk density and total porosity were measured for detecting the soil compaction ...
Dubravko Filipović +5 more
doaj
Model Tests on the Penetration Resistance of Bucket Foundations for Offshore Wind Turbines in Sand
Driven by the rapid development of offshore wind farms, bucket foundations have come to constitute a very promising form of foundation for offshore wind turbines, mainly owing to their efficient construction.
Hongyan Ding +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

