Results 101 to 110 of about 525,062 (269)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Efficient and Standardized Alarm Rationalization for Cybersecurity Monitoring
IEEE AccessThreat monitoring in cybersecurity systems is often jeopardized by alarm flooding, which frequently occurs in Security Information and Event Management (SIEM) solutions due to the unnecessary annunciation of numerous logs and event data from a variety of
Sarah Alabdulhadi, Ali Al-Matouq
doaj +1 more source
Research on Security Weakness Using Penetration Testing in a Distributed Firewall. [PDF]
Sensors (Basel), 2023 Tudosi AD +3 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Journal of Applied Informatics and ComputingWebsite security is one of the main concerns in the digital era, given the increasing potential for cyber threats. This research aims to improve website security by using the Vulnerability Assessment and Penetration Testing (VAPT) method that refers to ...
Diana Rohmaniah +3 more
doaj +1 more source
On protection of Freedom's solar dynamic radiator from the orbital debris environment. Part 1: Preliminary analyses and testing [PDF]
A great deal of experimentation and analysis was performed to quantify penetration thresholds of components which will experience orbital debris impacts.
Christiansen, Eric L. +2 more
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
, 2023 This slide deck provides a deep dive into penetration testing with a focus on the capabilities of Kali Linux. The slides begin with an overview and then divide into information gathering, vulnerability analysis, exploitation, and post-exploitation tools.
openaire +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source