Results 41 to 50 of about 525,062 (269)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Modelling and Intelligent Decision of Partially Observable Penetration Testing for System Security Verification

Systems
As network systems become larger and more complex, there is an increasing focus on how to verify the security of systems that are at risk of being attacked. Automated penetration testing is one of the effective ways to achieve this. Uncertainty caused by
Xiaojian Liu, Yangyang Zhang, Wenpeng Li, Wen Gu   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Depth of penetration effects in eddy current testing [PDF]

, 2012
The simple depth of penetration equation used for most eddy current calculations does not take into account the effect of the size of the coil or the effect of flaw morphology. The work described in this paper describes use of the CIVA eddy current model
Majidnia, S, Nilavalan, R, Rudlin, J
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Penetration Testing and Attack Automation Simulation: Deep Reinforcement Learning Approach [PDF]

مجلة جامعة النجاح للأبحاث العلوم الطبيعية
In this research, we propose a revolutionary deep reinforcement learning-based methodology for automated penetration testing. The suggested method uses a deep Q-learning network to develop attack sequences that effectively exploit weaknesses in a target ...
Ismael Jabr, Yanal Salman, Motasem Shqair, Amjad Hawash   +3 more
doaj   +1 more source

Symbiotic Analysis of Security Assessment and Penetration Tests Guiding Real L4 Automated City Shuttles

Telecom, 2023
The Connected Automated Vehicle (CAV)’s deployment is proof of the wide evolution of autonomous driving technologies enabling vehicles to gradually dispose of their drivers.
Meriem Benyahya, Pierre Bergerat, Anastasija Collen, Niels Alexander Nijdam   +3 more
doaj   +1 more source

Development of Comprehensive Subgrade Deflection Acceptance Criteria - Phase 3 Report [PDF]

, 2001
This report has presented the findings of Phase III of research conducted to aid in the development of subgrade deflection acceptance criteria for WisDOT.
Crovetti, James, Schabelski, Jay
core   +1 more source