Results 271 to 280 of about 159,023 (310)
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The Penicillins

Mayo Clinic Proceedings, 1987
The penicillins as a group are the most frequently and widely used of the antimicrobial agents because they are effective, low in toxicity, and relatively inexpensive. Effectiveness is due to the bactericidal action, the excellent distribution throughout the body spaces, and the wide spectrum of activity.
A J, Wright, C J, Wilkowske
openaire   +6 more sources

Evaluation and Management of Penicillin Allergy: A Review

Journal of the American Medical Association (JAMA), 2019
Importance &bgr;-Lactam antibiotics are among the safest and most effective antibiotics. Many patients report allergies to these drugs that limit their use, resulting in the use of broad-spectrum antibiotics that increase the risk for antimicrobial ...
E. Shenoy   +3 more
semanticscholar   +1 more source

The New Penicillins

New England Journal of Medicine, 1963
THE opening statement of Sir Alexander Fleming's1 paper describing his initial investigations of penicillin is as follows: While working with staphylococcus variants a number of culture-plates were...
Maxwell Finland, Jerome O. Klein
openaire   +5 more sources

THE PENICILLINS

Obstetrics and Gynecology Clinics of North America, 1992
The penicillins have played a major role in the treatment of many obstetric and gynecologic infections. The advent of the newer broad-spectrum penicillins has allowed their use as single-agent therapy for certain infections. Although toxicity is extremely low, disadvantages of their use include superinfection and induction of resistance.
B A, Campbell, S M, Cox
openaire   +2 more sources

Direct oral amoxicillin challenge without preliminary skin testing in adult patients with allergy and at low risk with reported penicillin allergy.

Allergy and Asthma Proceedings, 2019
Introduction: Ten percent of hospitalized patients report penicillin allergy; however, recent studies indicate that ∼98% of these patients are not acutely hypersensitive.
M. Kuruvilla   +3 more
semanticscholar   +1 more source

Documentation of penicillin adverse drug reactions in electronic health records: inconsistent use of allergy and intolerance labels

Internal medicine journal (Print), 2017
The majority of patients with penicillin allergy labels tolerate penicillins. Inappropriate avoidance of penicillin is associated with increased hospitalisation, infections and healthcare costs.
J. Inglis   +3 more
semanticscholar   +1 more source

Penicillin skin testing as an antimicrobial stewardship initiative.

American Journal of Health-System Pharmacy, 2017
PURPOSE An initiative to determine the effects of penicillin skin testing (PST) from an antimicrobial stewardship perspective is described. SUMMARY Penicillin allergy is one of the most frequently reported allergies; however, only about 10% of self ...
Bruce M. Jones, Christopher M. Bland
semanticscholar   +1 more source

Penicillin allergy—getting the label right

Drug and therapeutics bulletin, 2017
Penicillini allergy is a potentially serious adverse reaction that impacts on antibacterial treatment options. Although it is commonly reported and recorded in medical records, only a minority of patients with a label of penicillin allergy actually have ...
Penicillin allergy—getting
semanticscholar   +1 more source

Penicillin allergy: optimizing diagnostic protocols, public health implications, and future research needs.

Current Opinion in Allergy and Clinical Immunology, 2015
PURPOSE OF REVIEW Unverified penicillin allergy is being increasingly recognized as a public health concern. The ideal protocol for verifying true clinically significant IgE-mediated penicillin allergy needs to use only commercially available materials ...
E. Macy
semanticscholar   +1 more source

The Estimation of Penicillin K in Commercial Penicillin

Journal of the American Pharmaceutical Association (Scientific ed.), 1948
A method for the estimation of penicillin K in commercial penicillin together with its development, calculations, and results obtained on commercial samples is presented.
Donald C. Grove, William W Wright
openaire   +3 more sources

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