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Evaluation and Management of Penicillin Allergy: A Review

Journal of the American Medical Association (JAMA), 2019
Importance &bgr;-Lactam antibiotics are among the safest and most effective antibiotics. Many patients report allergies to these drugs that limit their use, resulting in the use of broad-spectrum antibiotics that increase the risk for antimicrobial ...
E. Shenoy   +3 more
semanticscholar   +1 more source

Direct oral amoxicillin challenge without preliminary skin testing in adult patients with allergy and at low risk with reported penicillin allergy.

Allergy and Asthma Proceedings, 2019
Introduction: Ten percent of hospitalized patients report penicillin allergy; however, recent studies indicate that ∼98% of these patients are not acutely hypersensitive.
M. Kuruvilla   +3 more
semanticscholar   +1 more source

Penicillins

Obstetrics and Gynecology Clinics of North America, 1989
Penicillins remain a class of antibiotics that are effective against various bacteria. Although newer penicillins continue to be developed and combinations of older penicillins with beta-lactamase inhibitors have become available, the use of these agents has not made them prohibitive for general use.
openaire   +2 more sources

The Penicillins

Medical Clinics of North America, 1987
Penicillin derivatives have an extraordinary track record of safety and efficacy since their introduction in the late 1940s. The in vitro activity, pharmacokinetics, adverse reactions, and clinical use of these agents are reviewed.
A J, Wright, C J, Wilkowske
openaire   +6 more sources

Penicillin therapy‐Newer semisynthetic penicillins

Clinical Pharmacology & Therapeutics, 1966
It is obvious that the perfect penicillin has not been developed as yet. There is need for an acid‐stable, highly absorbable, penicillinase‐resistant, broad‐spectrum penicillin. Progress, so far, has been exciting and most promising. Many agents are now heing studied, and many more will soon be available.
openaire   +2 more sources

THE PENICILLINS

Obstetrics and Gynecology Clinics of North America, 1992
The penicillins have played a major role in the treatment of many obstetric and gynecologic infections. The advent of the newer broad-spectrum penicillins has allowed their use as single-agent therapy for certain infections. Although toxicity is extremely low, disadvantages of their use include superinfection and induction of resistance.
B A, Campbell, S M, Cox
openaire   +2 more sources

Penicillin allergy

Clinical Pharmacology & Therapeutics, 1970
When the causes of penicillin allergy are fully understood, they might well offer answers to a number of immunochemical and biologie conundrums. Supperficially, there is no mystery in the fact that penicillin causes allergy‐lots of simple substances cause allergy‐the mystery comes when one considers that, of the millions of people who receive ...
openaire   +2 more sources

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