Results 181 to 190 of about 447,223 (260)

Drug supply shortages and their perceived consequences for patients: a questionnaire survey of German and Austrian physicians. [PDF]

Eur J Clin Pharmacol
Rotter JM, Seifert R.
europepmc   +1 more source

Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets

Advanced Materials Technologies, EarlyView.
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu, Qizheng Zhang, Tianli Hu, Juewen Liu, Hongxing Fu, Xin Zhao, Zijiang Yang, Chenjie Xu   +7 more
wiley   +1 more source

Implementing an Evidence-Based Guideline to Improve Perioperative Antimicrobial Prophylaxis Quality Among Patients With Penicillin Allergy Labels. [PDF]

Mayo Clin Proc Innov Qual Outcomes
Lessard S, Gonzalez-Estrada A, Porter SB, Edwards MA, Hamilton N, Andraschko K, Evans K, Sangaralingham L, Ridgeway JL, Challener D, Khan EH, Thao V, Welle S, Villavicencio A, Chang YH, Virk A.   +15 more
europepmc   +1 more source

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

Advanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann, Jessica Faber, Franz Moser, Alessandro Cianciosi, Nicoletta Murenu, Joachim Schenk, Katrin G. Heinze, Natascha Schaefer, Silvia Budday, Tomasz Jungst   +9 more
wiley   +1 more source

Global response to antibiotic exposure reveals a critical role for nucleotide metabolism in high-level β-lactam tolerance. [PDF]

NPJ Antimicrob Resist
Keller MR, Kazi MI, Saleh A, Basu U, Shin JH, Rhee K, Dörr T.   +6 more
europepmc   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Frequency and severity of systemic reactions during beta-lactam skin testing in adults with immediate hypersensitivity allergy. [PDF]

Allergy Asthma Clin Immunol
Letón-Cabanillas P, Noguerado-Mellado B, Quijada-Morales P, Salas-Parra G, Rojas-Pérez-Ezquerra P.   +4 more
europepmc   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

Advanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng, Torben A.B. van der Boon, Savannah Amy Haupt, Adam Jones, Yanjing Ji, Theo G. Van Kooten, Patrick van Rijn   +6 more
wiley   +1 more source

Emergence of Group B streptococcus with reduced susceptibility to penicillin in mainland China. [PDF]

New Microbes New Infect
Chen S, Li H, Zhang Y, Guo M, Yao K.
europepmc   +1 more source