Results 161 to 170 of about 10,097,740 (265)

Codocytosis in the Dog: 345 Cases (2020–2022)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker, Maria Jaramillo, Brad D. Cingolani, Floyd L. Williams Jr., Priscila B. S. Serpa, Andrew D. Woolcock   +5 more
wiley   +1 more source

Rational Design, Synthesis, and Biological Evaluation of New Substituted Dihydropyrimidinones as Antibacterial Agents and β-Lactamase Inhibitors. [PDF]

Chem Biol Drug Des
Soliman AM, Allam HA, Mahmoud WR, Naguib BH.   +3 more
europepmc   +1 more source

Isolation and Phylogenetic Analysis of Parapoxvirus orf From Outbreaks in Sheep in the Brazilian Midwest

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction This study aimed to isolate Parapoxvirus orf and characterize its genetic diversity through phylogenetic analysis in small ruminants from the state of Mato Grosso, Brazil. Methods A total of 103 scab samples were collected from sheep affected by nine contagious ecthyma outbreaks across three different mesoregions of Mato Grosso ...
Phelipe Magalhães Duarte, Maria de Nazaré Santos Ferreira, Amanda Marques Cordeiro, Sérgio Alves do Nascimento, Rita de Cássia Carvalho Maia, José Wilton Pinheiro Junior   +5 more
wiley   +1 more source

Temporal trends of inpatient oral penicillin challenges in a U.S. veteran cohort with a recorded penicillin allergy. [PDF]

Antimicrob Steward Healthc Epidemiol
Arasaratnam RJ, Vu C, Alvarez CA.
europepmc   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Calcium Imaging in H4IIE Liver Cells and Primary Rodent Hepatocytes: A Cost-Effective Protocol for Use With Fura-2 AM Ca²⁺ Indicator. [PDF]

Bio Protoc
Fang L, Habib AGK, Harris MD, Begley AJ, Ali ES.   +4 more
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

An epilepsy-associated KV3.1 potassium channel variant acts via dominant-positive effect. [PDF]

J Gen Physiol
Clatot J, Monnerie H, Panzer A, Platzer K, Goldberg EM.   +4 more
europepmc   +1 more source

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler, Noelia Jacobo‐Piqueras, Tamara Theiner, Ryoichi S. Taguchi, Laura E. Häfele, Marta Campiglio, Petronel Tuluc   +6 more
wiley   +1 more source

Statin-induced lipid carrier stress reveals a conserved vulnerability in β-lactam-resistant Gram-positive bacteria. [PDF]

Nat Commun
Torrens G, Bisset SW, López-Bravo M, Johansson AF, Lopez D, Cava F.   +5 more
europepmc   +1 more source