Results 91 to 100 of about 33,588 (309)
Magazine reporting on the activities and programs of the University Hospital at Boston University Medical ...
Office of Publication Services, Boston University Medical Center
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Genomic and non-genomic effects of androgens in the cardiovascular system: clinical implications [PDF]
The principle steroidal androgens are testosterone and its metabolite 5α-dihydrotestosterone (DHT), which is converted from testosterone by the enzyme 5α-reductase.
Ahmed, S. Faisal+4 more
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Penile Cancer: the importance of Prevention [PDF]
Although rare in developed countries (0.2 cases cases/100 000 men) (1), penile cancer (PC) is com-mon in underdeveloped countries. In Brazil, Paraguai, Angola and India, the incidence of PC varies from 2.3 to 8.3 cases/100 000 men) (2,3). In Brazil annually around 1000 penile amputations are reported.
openaire +4 more sources
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu+18 more
wiley +1 more source
Androgen and estrogen receptor expression in the developing human penis and clitoris. [PDF]
To better understand how the human fetal penis and clitoris grows and remodels, we undertook an investigation to define active areas of cellular proliferation and programmed cell death spatially and temporally during development of human fetal external ...
Baskin, Laurence+6 more
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BackgroundSquamous cell cancer of the penis is an uncommon, aggressive malignancy whit an age-adjusted annual incidence of one out of every 100,000 men. Surgical amputation (penectomy) has been considered the gold standard for the treatment of penile cancer, but is associated with a high level of psychosexual morbidity. Low-dose-rate brachytherapy (BT)
openaire +2 more sources
Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells
A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga+13 more
wiley +1 more source
Penile Carcinoma: Risk Factors and Molecular Alterations
Penile carcinoma is a rare, male cancer. Although the incidence of penile carcinoma is very low in Western countries, in some countries, the incidence is significantly greater, with penile carcinoma accounting for ≤10% of all male malignancies.
Marilia F. Calmon+3 more
doaj +1 more source
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal+15 more
wiley +1 more source
The mechanism diagram reveals that the formation of trauma‐induced heterotopic ossification (HO) is accompanied by the polarization of macrophages toward the M1 phenotype. Additionally, the extracellular vesicles secreted by M1 macrophages, which contain periostin (POSTN), directly bind to PTK7 in tendon‐derived stem cells (TDSCs).
Hang Liu+9 more
wiley +1 more source