Results 81 to 90 of about 33,588 (309)
Spatial Coordination Structure‐Driven Enzyme‐Like Selectivity in Single‐Atom Nanozymes
Sun et al. reviews recent progress in enhancing the enzyme‐like catalytic selectivity of SAzymes through the rational design of their spatial coordination structures. They emphasize the structure‐activity relationships of various attributes of these coordination structures in promoting selective catalytic behavior, the strategic design of coordination ...
Qijun Sun+6 more
wiley +1 more source
A 58-year-old Caucasian male presented to the urology clinic reporting an approximate one-year history of a persistent irritating, slowly progressive, glans penis redness. Biopsy revealed penile squamous cell carcinoma in situ.
Deirdre Mary Fanning, Hugh Flood
doaj +1 more source
Nanostructured Protein Surfaces Inspired by Spider Silk
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
Aberrant CEACAM19 expression is associated with metastatic phenotype in penile cancer
Xiheng Hu,1 Mingfeng Chen,1 Yangle Li,1 Yin Wang,2 Sailan Wen,2 Fu Jun3 1Department of Urology, Xiangya Hospital, Central South University, Changsha, Human 410008, P.R. China; 2Department of Pathology, Xiangya Hospital, Central South University, Changsha,
Hu X, Chen M, Li Y, Wang Y, Wen S, Jun F
doaj
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk+8 more
wiley +1 more source
Prognostic Factors in Penile Cancer
To review the published data concerning the prognostic factors in patients with penile squamous cell carcinoma (SCC).We performed an extensive literature search using the MEDLINE databases. Multiple "free text" searches were performed, searching for the following terms individually in the fields title and abstract of the records: "squamous cell ...
FICARRA, VINCENZO+4 more
openaire +5 more sources
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang+9 more
wiley +1 more source
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi+15 more
wiley +1 more source
The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong+27 more
wiley +1 more source