Results 61 to 70 of about 3,009,633 (302)

Current and Future Strategies in the Diagnosis and Management of Penile Cancer

open access: yesAdvances in Urology, 2011
Penile cancer is an uncommon malignancy that has a devastating effect on the patient while also being challenging to diagnose and treat. By implementing preventive measures, we can decrease the incidence of this disease and improve the quality of life of
Samuel M. Lawindy   +3 more
doaj   +1 more source

High-Dose-Rate Brachytherapy as an Organ-Sparing Treatment for Early Penile Cancer

open access: yes, 2022
Background: Low-dose-rate brachytherapy is an effective organ-sparing treatment for patients with early-stage penile cancer. However, only limited data are available on the role of high-dose-rate brachytherapy (HDR-BT) in this clinical setting.
Lukáš Holub   +21 more
core   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano   +10 more
wiley   +1 more source

Genomic profiling of human penile carcinoma predicts worse prognosis and survival

open access: yes, 2015
The molecular mechanisms underlying penile carcinoma are still poorly understood, and the detection of genetic markers would be of great benefit for these patients. In this study, we assessed the genomic profile aiming at identifying potential prognostic
Busso-Lopes, Ariane Fidelis   +18 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

open access: yesAdvanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion   +10 more
wiley   +1 more source

Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer

open access: yesUrology Case Reports, 2019
Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue.
Cam Nguyen   +5 more
doaj   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

open access: yesAdvanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang   +7 more
wiley   +1 more source

Diagnosis and management of premalignant penile lesions

open access: yesTherapeutic Advances in Urology, 2011
Diagnosing premalignant penile lesions from benign penile dermatoses presents a unique challenge. The rarity of these conditions and the low incidence of penile cancer mean that the majority of our knowledge is based on small, non-randomized ...
Majid Shabbir, Suks Minhas, Asif Muneer
doaj   +1 more source

Performance and Environmental Impact of Flexible Temperature Sensors on Cellulose‐Based Substrate

open access: yesAdvanced Electronic Materials, EarlyView.
Toward low‐environmental‐impact approach to thin‐film sensors fabrication using natural ingredient‐based triacetyl cellulose (TAC) substrate. Temperature sensors are fabricated and characterized based on thermal and mechanical performance. Substrate recovery is demonstrated by facile dissolution of a Mo‐based sensor in deionized water.
Dianne C. Corsino   +14 more
wiley   +1 more source

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