Results 51 to 60 of about 17,826 (255)

PENILE CANCER AND OUR EXPERIENCE AT TERTIARY CARE HOSPITAL

open access: yesJournal of Cancer and Allied Specialties, 2017
Purpose: Penile cancer is a rare malignancy which accounts for
M Fahd Shah   +5 more
doaj   +1 more source

A Low‐Cost, Handheld Optical Stiffness Sensor for Minimally Invasive Surgery

open access: yesAdvanced Robotics Research, EarlyView.
A novel handheld stiffness sensor is presented for real‐time tissue stiffness characterization. By simultaneously sensing contact force and tissue deformation, the device enables accurate stiffness quantification without requiring precise manual control. This approach offers a promising solution for intraoperative tumor detection and minimally invasive
Qianyu Ma   +4 more
wiley   +1 more source

SPP1 is associated with adverse prognosis and predicts immunotherapy efficacy in penile cancer

open access: yesHuman Genomics, 2023
Background The effect of SPP1 in squamous cell carcinoma of the penis (PSCC) remained unknown. We attempted to clarify the function of the SPP1 gene in PSCC.
Yuantao Zou   +8 more
doaj   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

Localized Accumulation of Tri‐n‐Propylamine Prolongs Electrochemiluminescence for Tumor Model Spheroid Analysis

open access: yesAngewandte Chemie, EarlyView.
Here, we enhance the electrochemiluminescence imaging of cellular spheroids using [Ru(bpy)3]2+/TPrA chemistry. Our strategy, which involves pre‐incubation with TPrA, enables high‐resolution, long‐term visualization of cellular spheroids without phototoxicity.
Vanshika Gupta   +5 more
wiley   +2 more sources

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Characteristics of Penile Cancer at Tertiary Centre Hospital: A Nine Years Study from 2010-2019

open access: yesIndonesian Journal of Cancer, 2022
Background: Penile cancer is a rare and aggressive disease. The incidence in India, Africa, and South America ranges from 2.3 to 8.3 per 100,000. No data regarding incidence rates in Indonesia.
Christopher Kusumajaya, Ferry Safriadi
doaj   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Current and Future Strategies in the Diagnosis and Management of Penile Cancer

open access: yesAdvances in Urology, 2011
Penile cancer is an uncommon malignancy that has a devastating effect on the patient while also being challenging to diagnose and treat. By implementing preventive measures, we can decrease the incidence of this disease and improve the quality of life of
Samuel M. Lawindy   +3 more
doaj   +1 more source

Recent advances in the management of penile cancer [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Penile cancer is a rare condition and can be very complex to manage. Advances in surgical techniques, imaging, pathological classification and patient pathways have led to improved patient care.
Maximilian J Johnston, Raj Nigam
doaj   +1 more source

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