Results 181 to 190 of about 18,088 (262)

Sensing‐Integrated Patient‐Derived Tumorspheres Predict Chemotherapeutic Efficacy via Local Extracellular pH Dynamics

Small, EarlyView.
The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti, Valentina Onesto, Anna Chiara Siciliano, Helena Iuele, Stefano D'Ugo, Norma Depalma, Cinzia Fasano, Alessandro D'Amuri, Giuseppe Gigli, Marcello G. Spampinato, Loretta L. del Mercato   +10 more
wiley   +1 more source

Case Report: First In-Human Report of Cure of Refractory <i>Mycoplasma genitalium</i> Infection With Omadacycline. [PDF]

Open Forum Infect Dis
Patel NM.
europepmc   +1 more source

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

Association between visceral adiposity index and arteriogenic erectile dysfunction: a multicenter cross-sectional study. [PDF]

Sex Med
Mei Y, Zhao H, Ji N, Liu Y, Zhang G, Chen Y, Xu R, Zhang W, Lu H, Xue D, Zhuang Q, Feng X.   +11 more
europepmc   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

Environmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff, Jessica Reinert, Silke Steinborn, Marion Berger, Judith Neuhoff, Lennart Marske, Kerttu Valtanen, Udo Jäckel, Stefanie Klar   +8 more
wiley   +1 more source

Immune-mediated skin diseases and erectile dysfunction: mechanisms and multidisciplinary management. [PDF]

Front Immunol
Lv C, Cao H, Zhao D, Yang Y, Ma Z, Zhang Y, Wu X, Chen M, Gao J.   +8 more
europepmc   +1 more source

Preoperative caudal blocks associated with decreased cumulative opioid requirements compared to postoperative caudal blocks in pediatric urologic surgery

UroPrecision, EarlyView.
Abstract Background Caudal blocks (CB) are a cornerstone of pediatric urologic surgery, providing effective analgesia while mitigating potential neurotoxicity associated with general anesthesia and opioids. However, the optimal timing of CB—preoperative versus postoperative—remains controversial.
Jordan L. Mendelson, William Brenseke, Diego Alvarez Vega, William Nguyen, Mohammed Shium, Saige Gitlin, Ronnie G. Fine, Steven C. Friedman, Mark Horowitz, Walter I. Weiss, Raghu Idupuganti, Jordan S. Gitlin   +11 more
wiley   +1 more source

Adverse events following HPV vaccine reported to the Vaccine Adverse Event Reporting System. [PDF]

PLoS One
Zhang S, Li Y, Liu M, Yang J, Wang X, Wang M.   +5 more
europepmc   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

UroPrecision, EarlyView.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega, Mariela R. Martinez, Steven Friedman, Tehilla Adams, Jordan L. Mendelson, William Nguyen, Jordan S. Gitlin   +6 more
wiley   +1 more source

Search for Equus caballus papillomavirus type 2 in tissues of asymptomatic horses in southern brazil. [PDF]

Braz J Microbiol
Santi EMT, Pecego JB, Schirmer MFA, Vargas TP, Marcus VB, de Vargas I, Kommers GD, Cocco M, Michelon NF, Flores EF, Flores MM.   +10 more
europepmc   +1 more source