Results 61 to 70 of about 9,052,975 (401)

Erectile dysfunction - an update of current practice and future strategies [PDF]

open access: yes, 2013
Erectile dysfunction (ED) is defined as the inability to achieve and maintain a penile erection adequate for satisfactory sexual intercourse.1 Up to 150 million men worldwide suffer from ED and this figure is likely to double by the year 2025.2 A number
Kalsi, J, Muneer, A
core   +1 more source

Long-Term Results after Surgical Treatment of Congenital Penile Curvature Using a Modified Nesbit Technique

open access: yesThe World Journal of Men's Health, 2020
Purpose: Congenital penile curvature (CPC) is a rare condition with surgical correction being the standard therapy. In the current study, we report long-term results analyzing the surgical and functional outcomes using a modified Nesbit technique ...
Ioannis Sokolakis   +6 more
doaj   +1 more source

Fraction-variant beam orientation optimization for non-coplanar IMRT [PDF]

open access: yes, 2017
Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously optimizes non-coplanar beam angles for all fractions, yielding a fraction-variant (FV) treatment plan.
arxiv   +1 more source

Penile Mondor's disease- an understated entity

open access: yesUrology Case Reports, 2020
We present a case of Penile Mondor's Disease (PMD) in a 36-year old male patient. PMD is an under-recognised and uncommon condition which presents with pain on erection and cord-like thickening of the dorsum of the penis. The diagnosis of PMD is usually confirmed with ultrasound imaging.
Jeremy Wild, Liam Wilson, Mohit Bajaj
openaire   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Penile eruptive syringoma

open access: yesThe Pan African Medical Journal, 2017
A 23-year-old man presented with a six-year history of asymptomatic papular lesions on the penis. He had no history of sexually transmitted disease and reported having sought dermatologic care because he was beginning a relationship and his new ...
Fred Bernardes Filho   +1 more
doaj   +1 more source

Penile cancer trends and economic burden in the Brazilian public health system

open access: yesEinstein (São Paulo), 2020
Objective: To gather information on penile cancer epidemiologic trends and its economic impact on the Brazilian Public Health System across the last 25 years.
Fernando Korkes   +6 more
doaj   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

An unanswered question in pediatric urology: the post pubertal persistence of prepubertal congenital penile curvature correction by tunical plication

open access: yesInternational Brazilian Journal of Urology
Objective: The aim of this study is to analyze post pubertal results of pre pubertal tunica albuginea plication with non-absorbable sutures in the correction of CPC.
Ünsal Ozkuvanci   +6 more
doaj   +1 more source

Patient Perceptions of Medication Therapy for Prevention of Posttraumatic Osteoarthritis Following Anterior Cruciate Ligament Injury: A Qualitative Content Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell   +10 more
wiley   +1 more source

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