Results 51 to 60 of about 18,749 (299)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Male external genitalia growth curves and charts for children and adolescents aged 0 to 17 years in Chongqing, China

Asian Journal of Andrology, 2018
Genital size is a crucial index for the assessment of male sexual development, as abnormal penile or testicular size may be the earliest visible clinical manifestation of some diseases.
Yi-Nan Wang, Qing Zeng, Feng Xiong, Yan Zeng   +3 more
doaj   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

Advanced Healthcare Materials, EarlyView.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao, Akhila Naru, Dhanush Gandavadi, Mengxi Zheng, Saraswathi Lanka, Hyeongjun Cho, Chau Nguyen Minh Hoang, Jianqiang Zhang, Ying Fang, Xing Wang   +9 more
wiley   +1 more source

Human penile ossification: case report

São Paulo Medical Journal, 2007
CONTEXT: Ossification in the human penis is such a rare condition that only 34 histologically evident cases have previously been reported. Among several conditions that have been correlated with this problem the most frequent is Peyronie disease.
Homero Oliveira de Arruda, Hudson de Lima, Valdemar Ortiz   +2 more
doaj   +1 more source

Inflatable penile prosthesis and penile plication in patients with Peyronie’s disease

Journal of Visualized Surgery, 2020
The surgical gold standard treatment for severe erectile dysfunction (ED) is inflatable penile prosthesis (IPP). During IPP placement, penile curvature can also be addressed, and may be corrected in up to 90% of cases with inflation alone. However, for severe deformities, adjunctive maneuvers are needed. Our preference is to place plicating sutures for
Juan D. Cedeno, Billy H. Cordon
openaire   +1 more source

HPV infections and flat penile lesions of the penis in men who have sex with men

, 2019
Background: Flat penile lesions (FPL) in heterosexual men are thought to play a role in the transmission of HPV. We investigated the association between FPL and penile HPV, and explored determinants of FPL in men who have sex with men (MSM).
Schim van der Loeff, Maarten F., Meijer, Chris J. L. M., Bruisten, Sylvia M., Sylvia Bruisten, Chris Meijer, Henry De Vries, Maaike Bleeker, Wilma Brokking, Brokking, Wilma, de Vries, Henry J. C., Alexandra Kovaleva, King, Audrey J, Bruisten, Sylvia M, Maarten Schim Van Der Loeff, Audrey King, Bleeker, Maaike C. G., Meijer, Chris J L M, van Bilsen, Ward P. H., Kovaleva, Alexandra, King, Audrey J., De Vries, Henry J C, Schim Van Der Loeff, Maarten F, Bleeker, Maaike C G, Ward Van Bilsen, Van Bilsen, Ward P H   +24 more
core   +1 more source

A rare complication of a malleable penile prosthesis: migration to the thigh region [PDF]

, 2013
Guner, Bayram/0000-0001-7602-2255WOS: 000326878200038PubMed: 24013620Dear editor, Here, we discuss an unusual prosthesis migration to the thigh region.
Ö reden, Ercan, Güner, Bayram, Benli, Erdal   +2 more
core   +1 more source