Results 111 to 120 of about 555,805 (243)

STIM1/Orai1-mediated store-operated Ca2+ entry: the tip of the iceberg [PDF]

, 2011
Highly efficient mechanisms regulate intracellular calcium (Ca2+) levels. The recent discovery of new components linking intracellular Ca2+ stores to plasma membrane Ca2+ entry channels has brought new insight into the understanding of Ca2+ homeostasis ...
CARNEIRO, F.S., GIACHINI, F.R., HANNAN, J., LIMA, V.V., TOSTES, R.C., WEBB, R.C.   +5 more
core   +3 more sources

[Penile metastasis of bladder cancer].

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 1993
The Authors mark a case of penile metastasis in a man 70 years old suffering from bladder cancer. They emphasize the rarity of this manifestation. They discuss about symptomatology, diagnosis and pathogenesis even today debated. They mark therapeutical indications about the short expectation of life, that these patients have from appearance of the ...
G P, Manca, P P, Piras, G, Martina, P P, Bordoni, M, D'Alpaos, F, Andreassi   +5 more
openaire   +1 more source

Calycosin Targets the CYP1B1‐AKT/SP1‐GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis

Phytotherapy Research, EarlyView.
Mechanism of Calycosin in Regulating Ferroptosis in Colorectal Cancer via Binding to CYP1B1. ABSTRACT Calycosin, a natural flavonoid small‐molecule compound derived from traditional Chinese medicine, has demonstrated remarkable pharmacological activity in the field of cancer therapy.
Lihan Bie, Xin Lei, Di Wu, Yang Zhang, Chengshan He, Luyao Liu, Jiawei Zhou, Xin Zhou, Yingying Lu, Zheng Xu   +9 more
wiley   +1 more source

Penile Metastasis from Anal Canal Carcinoma: A Case Report

Journal of Urological Surgery
Penile metastases are exceptionally rare and are associated with poor prognosis. Herein, we report the case of a 74-year-old man with previously treated squamous cell carcinoma of the anal canal who was referred with a painless penile lump.
António Modesto Pinheiro, Filipa Pereira, Sara Duarte, Eduardo Felício, Guilherme Bernardo, Filipe Gaboleiro, André Barcelos, Sónia Ramos, Alberto Silva, Andrea Furtado, Fernando Ribeiro, Pepe Cardoso, Fernando Ferrito   +12 more
doaj   +1 more source

Evidence-based indications for the planning of PET or PET/CT capacities are needed [PDF]

, 2019
Purpose To identify evidence-based indications for PET/PET–CT scans in support of facilities planning and to describe a pilot project in which this information was applied for an investment decision in an Austrian region.
Busse, Reinhard, Ferch, Manfred, Fuchs, Sabine, Grössmann, Nicole, Wild, Claudia   +4 more
core   +1 more source

Priapism secondary to penile metastasis of rectal cancer

World Journal of Gastroenterology, 2009
Metastatic penile carcinoma is rare and usually originates from genitourinary tumors. The presenting symptoms or signs have been described as nonspecific except for priapism. Rectal adenocarcinoma is a very unusual source of metastatic penile carcinoma. We report a case of metastatic penile carcinoma that originated from the rectum.
Ji Chan, Park, Wook Hyun, Lee, Min Kyu, Kang, Suk Young, Park   +3 more
openaire   +2 more sources

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

Andrology, EarlyView.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani, María Otero‐Alén, Juan Suárez‐Quintanilla, Marina Gándara‐Cortés, Tomás García‐Caballero, Rosalía Gallego, Lucía García‐Caballero   +6 more
wiley   +1 more source

Penile metastasis from rectal carcinoma.

Saudi medical journal, 2001
We are presenting a 65-year old patient with metastatic carcinoma of the penis which was discovered 19 months after abdomino-perineal resection for rectal cancer (Duke A). There was also metastasis in the perineum and one rib. Penile biopsy and cavernosography were carried out and established the metastatic nature.
F, Al-Mashat, A, Sibiany, S, Rakha, F, Olumide   +3 more
openaire   +1 more source

Tumour progression shows decrease in PD‐L1 expression in matched metastases/primary uveal melanomas

Acta Ophthalmologica, EarlyView.
Abstract Purpose Immune checkpoint inhibitors (ICI) have revolutionised the treatment of several malignancies. However, the results of ICI therapy remain unsatisfactory in metastatic uveal melanoma (UM). We analysed the expression of PD1, PD‐L1, T‐cell and macrophage markers in a set of matched primary and metastatic UM in an attempt to better ...
Maria Chiara Gelmi, Gulçin Gezgin, Ellen Kapiteijn, T. H. Khanh Vu, Martine J. Jager, Robert M. Verdijk   +5 more
wiley   +1 more source

TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

The FEBS Journal, EarlyView.
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni, Lucia Merolle, Agnese Razzoli, Eleonora Maurizi, Gaia Gavioli, Roberto Baricchi, Chiara Marraccini, Davide Schiroli   +7 more
wiley   +1 more source