Results 71 to 80 of about 8,190 (251)

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

open access: yesAdvanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo   +13 more
wiley   +1 more source

Penile and multiple cutaneous metastases over the pubic region from a rectal adenocarcinoma: An uncommon case

open access: yesTzu Chi Medical Journal, 2018
Synchronous penile and multiple cutaneous metastases over the pubic region from a rectal adenocarcinoma are rare, and they usually indicate widespread disease. The most frequent localization of cutaneous metastases is the postoperative scar. Simultaneous
Vipul D Yagnik
doaj   +1 more source

Genital Skin Diseases and Their Expression in Sexual Functionality [PDF]

open access: yes, 2015
Sexual functionality acts as an important function of the individual, acting both physically and mentally to create a state of well-being and permitting procreation.
Albu, Gabriela   +3 more
core   +2 more sources

Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo

open access: yesAdvanced Functional Materials, EarlyView.
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić   +9 more
wiley   +1 more source

Mechanobiologically Engineered Mimicry of Extracellular Vesicles for Improved Systemic Biodistribution and Anti‐Inflammatory Treatment Efficacy in Rheumatoid Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Triblock copolymer‐reinforced liposomal mimics of extracellular vesicles are engineered with tunable membrane elasticity. A semi‐elastic formulation (Tri‐ARTEX8:2) co‐encapsulating stem cell cytosolic extract and AntagomiR155 targets inflamed joints via the ELVIS effect, reprograms macrophages from M1 to M2, and markedly alleviates collagen‐induced ...
Dahwun Kim   +11 more
wiley   +1 more source

Characteristic of penile cancer and prognostic factors of inguinal and pelvic lymph node involvement

open access: yesUrology Annals, 2023
Background: Penile cancer is a rare malignancy which inguinal and pelvic lymph node involvement plays a major role in patients' survival. The prognosis of patients with lymph node metastasis is poorer.
Kritanu Kultravut, Satit Siriboonrid
doaj   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

open access: yesAdvanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr.   +3 more
wiley   +1 more source

Penile cancer metastasizing to the breast: a case report [PDF]

open access: yes, 2016
BACKGROUND: Penile cancer is a relatively uncommon cancer in developed nations. Metastatic disease is rare, but lymphatic or vascular spreading has been previously reported to the liver, lungs, bones, brain, heart and skin.
Alba Di Leone   +7 more
core   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

open access: yesAdvanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Human Papilloma Virus: Prevalence, distribution and predictive value to lymphatic metastasis in penile carcinoma

open access: yesInternational Brazilian Journal of Urology, 2013
Objectives To evaluate the prevalence, distribution and association of HPV with histological pattern of worse prognosis of penile cancer, in order to evaluate its predictive value of inguinal metastasis, as well as evaluation of other previous reported ...
Aluizio Goncalves da Fonseca   +4 more
doaj   +1 more source

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