Results 91 to 100 of about 5,528 (259)
What's New? Immune suppression induced by HIV infection significantly increases the risk of certain cancers among people with HIV (PWH). In the present study, the authors investigated cancer incidence among HIV‐infected individuals in Italy using data from the Italian Cohort Naïve Antiretrovirals. Comparison with the corresponding general population in
Pierluca Piselli+243 more
wiley +1 more source
Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley +1 more source
What's New? Adoptive cell therapy (ACT) with tumor antigen‐specific CD8+ T cells has shown success in clinical trials treating patients with advanced or metastatic melanoma. Here, the authors established protocols for generating CD8+ T cells from human induced pluripotent stem cells (hiPSCs) expressing a melanoma‐specific T cell receptor (TCR) or ...
Juliane Poelchen+13 more
wiley +1 more source
Pregnancy via Testicular Sperm Extraction for Anejaculation After Neuroblastoma Surgery
ABSTRACT Background Surgical treatment of a neuroblastoma, a malignant tumor of the sympathetic nervous system, may result in ejaculatory disorder. There are no reports examining ejaculation disorders after neuroblastoma surgery. Case Presentation The patient was a 31‐year‐old Japanese male who had undergone surgery for neuroblastoma of the abdomen at ...
Jurii Karibe+8 more
wiley +1 more source
Epidemiology of penile cancer in Poland compared to other European countries
Objectives To examine the epidemiology of penile cancer in Poland compared to other European countries. Materials and Methods Incidence and mortality data were acquired from the national cancer registries in Europe and WHO Mortality Database ...
Iwona Wnętrzak+6 more
doaj +1 more source
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor+3 more
wiley +1 more source
Genital Crohn's disease in pediatrics and genetic associations
Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang+5 more
wiley +1 more source
Background and Objectives: To investigate the role of preoperative albumin-to-alkaline phosphatase ratio (AAPR) in predicting pathologic node-positive (pN+) disease in penile cancer (PC) patients undergoing inguinal lymph node dissection (ILND ...
Antonio Tufano+9 more
doaj +1 more source
Sexually transmitted infections caused by the human papillomavirus (HPV) are the most prevalent in the world and can cause from genital warts to premalignant lesions, which can lead to cervical cancer, vaginal and vulvar neoplasms, anal and penile ...
Marília Barcelos Marqui+5 more
doaj
Polypept(o)ide‐Based Core–Shell Bottlebrush Polymers: A Versatile Platform for Drug Encapsulation
This study developed polypept(o)ide‐based core–shell brushes (CSBs) with tunable sizes (Rh: 17–70 nm) for hydrophobic drug delivery. CSBs achieved 10% dasatinib loading through π–π interactions, enabling sustained release over 72 h. Notably, CSB‐dasatinib complexes showed comparable cell viability reduction to the free drug in U‐87 MG cells ...
Bonan Zhao+6 more
wiley +1 more source