Results 41 to 50 of about 388,358 (308)

Application of Human Amniotic Membrane in Canine Penile Tunica Albuginea Defect: First Step toward an Innovating New Method for Treatment of Peyronie?s Disease

International Brazilian Journal of Urology, 2014
Purposes To evaluate the efficacy of human amniotic membrane (AM) grafting in the canine penile tunica albuginea defect; we developed an animal model as the first step toward an innovating new method for the treatment of Peyronie’s disease, penile ...
M. Salehipour, K. Izadpanah, A. Safaei, M. Kamranpoor, Farsiani M.R.   +4 more
doaj   +1 more source

Penile melanoma

Brazilian Journal of Oncology, 2021
Penile melanoma is a rare event, responsible for less than 1.4% of penile cancers. In general, it is late diagnosed and the treatment is usually aggressive.
Luiz Felipe de Mello Pereira Leitão, Fernanda Monteiro Orellana, João Pedro Vaz de Souza Cabral Simões, Rute Facchini Lellis, Marcus Maia, Roni de Carvalho Fernandes, Luis Gustavo Morato de Toledo   +6 more
doaj   +1 more source

Prostate lymphoscintigraphy and radio-guided surgery for sentinel lymph node identification in prostate cancer - Technique and results of the first 350 cases [PDF]

, 2003
Introduction: Having in mind the promising results of lymphoscintigraphy and intraoperative gamma probe application for the detection of sentinel lymph nodes (SLN) in malignant melanoma, breast and penis cancer, we tried to identify the SLN in prostate ...
Graf, Gerhard, Hamm, Michael, Harzmann, Rolf, Heidenreich, Peter, Keil, Mathias, Vogt, Harry, Wawroschek, Friedhelm, Weckermann, Dorothea, Wengenmair, Hermann   +8 more
core   +1 more source

Hospitalization burden associated with anus and penis neoplasm in Spain (2016-2020)

Human Vaccines & Immunotherapeutics
In 2020, there were approximately 50,865 anal cancer cases and 36,068 penile cancer cases worldwide. HPV is considered the main causal agent for the development of anal cancer and one of the causal agents responsible for the development of penile cancer.
Victor Fernandez-Alonso, Ruth Gil-Prieto, Maria Amado-Anton-Pacheco, Valentín Hernández-Barrera, Ángel Gil-De-Miguel   +4 more
doaj   +1 more source

Deep Inguinal Lymph Node Metastases Can Predict Pelvic Lymph Node Metastases and Prognosis in Penile Squamous Cell Carcinoma

Frontiers in Oncology, 2021
ObjectivesTo evaluate the relationship between deep inguinal lymph node metastasis (ILNM) and pelvic lymph node metastasis (PLNM) and explore the prognostic value of deep ILNM in penile squamous cell carcinoma (PSCC).Materials and MethodsThe records of ...
Zhenyu Yang, Zhenyu Yang, Zhenyu Yang, Xingliang Tan, Xingliang Tan, Xingliang Tan, Yanjun Wang, Yanjun Wang, Yanjun Wang, Yuantao Zou, Yuantao Zou, Yuantao Zou, Dong Chen, Dong Chen, Dong Chen, Zhiming Wu, Zhiming Wu, Zhiming Wu, Zhuowei Liu, Zhuowei Liu, Zhuowei Liu, Yonghong Li, Yonghong Li, Yonghong Li, Zike Qin, Zike Qin, Zike Qin, Hui Han, Hui Han, Hui Han, Fangjian Zhou, Fangjian Zhou, Fangjian Zhou, Kai Yao, Kai Yao, Kai Yao   +35 more
doaj   +1 more source

Surgical Management of Penile and Preputial Neoplasms in Equine with Special Reference to Partial Phallectomy [PDF]

Journal of Veterinary Medicine, 2013
Penile and preputial neoplasia in horses occurs infrequently and represents diagnostic and therapeutic challenges. The present study was carried out on a total number of 21 equids (14 stallions and 7 donkeys) suffered from different penile and preputial neoplasia.
Awad Rizk, Esam Mosbah, Gamal Karrouf, Mohamed Abou Alsoud   +3 more
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Prognostic Markers and Trials in Penile Cancer

Urology Research and Practice, 2023
New tumor biomarkers open the potential for designing personalized therapy for penile squamous cell carcinoma. Despite the initial promising results of some biomarkers, controversy remains due to contradictory studies.
Naufal Naushad, Abdalla A. Deb, Ayman A. Agag, Hosam A. Serag, Vijay K. Sangar   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source