Results 51 to 60 of about 388,358 (308)

Nursing Intervention Strategy Oriented to Continuous Care in Patients with Prostate Cancer

Revista Finlay, 2022
Background: prostate cancer is considered a worldwide health problem that affects elderly and black men more frequently. Objective: to develop a nursing intervention strategy to improve the health care of patients diagnosed with prostatic and penile ...
Nairovys Gómez Martínez, Riber Fabian Donoso Norona, Germania Elizabeth Vilema Vizuete   +2 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Penile metastasis from primary cholangiocarcinoma: the first case report [PDF]

, 2013
BACKGROUND: Metastatic penile carcinoma derived from cholangiocarcinoma (CCA) has not been previously reported in the literature. Common metastatic sites for CCA include the regional lymph nodes and adjacent organs.
Andrea Fuschi, Antonio Carbone, Antonio Luigi Pastore, Carlo Della Rocca, Claudio Di Cristofano, Cristina Maggioni, Davide Moschese, Domenico Alvaro, Domenico De Santis, Giorgia Manfredonia, Giovanni Palleschi, Natale Porta, Piero Maceroni, Simone Ferretti, Vincenzo Petrozza, Yazan Al Salhi   +15 more
core   +1 more source

A comprehensive review of current knowledge on penile squamous cell carcinoma

Frontiers in Oncology
Neoplasm of the penis is relatively rare in most regions representing 0-2% of cancers worldwide. While the penis can be affected by sarcomas, basal cell carcinomas or even melanoma, Penile Squamous Cell Carcinoma (PSCC) represents approximately 95% of ...
Nishanth Thumma, Neharaj Pitla, V. Gorantla, M. du Plessis   +3 more
semanticscholar   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Twenty-two-year incidence trend of urological cancers in the Republic of Korea: 1999–2020 [PDF]

Investigative and Clinical Urology
Purpose: Cancer is a disease with high social costs, and policymaking through accurate statistics is very important. This study presents the national cancer statistics on the incidence of urological cancers in the Republic of Korea over 22 years, from ...
Seunghyeon Cho, Won-Ju Park
doaj   +1 more source

Warty–basaloid carcinoma: clinicopathological features of a distinctive penile neoplasm. Report of 45 cases [PDF]

Modern Pathology, 2010
Most penile cancers are squamous cell carcinomas, but there are several subtypes with different clinicopathologic, viral, and outcome features. We are presenting 45 cases of a distinctive morphological variant of penile squamous cell carcinoma composed of mixed features of warty and basaloid carcinomas.
Alcides, Chaux, Pheroze, Tamboli, Alberto, Ayala, Fernando, Soares, Ingrid, Rodríguez, José, Barreto, Antonio L, Cubilla   +6 more
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Pre-referral GP consultations in patients subsequently diagnosed with rarer cancers: a study of patient-reported data. [PDF]

, 2016
BACKGROUND: Some patients with cancer experience multiple pre-diagnostic consultations in primary care, leading to longer time intervals to specialist investigations and diagnosis.
Abel, GA, Lyratzopoulos, G, Mendonca, SC
core   +5 more sources