Results 51 to 60 of about 349,677 (327)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Nursing Intervention Strategy Oriented to Continuous Care in Patients with Prostate Cancer

Revista Finlay, 2022
Background: prostate cancer is considered a worldwide health problem that affects elderly and black men more frequently. Objective: to develop a nursing intervention strategy to improve the health care of patients diagnosed with prostatic and penile ...
Nairovys Gómez Martínez, Riber Fabian Donoso Norona, Germania Elizabeth Vilema Vizuete   +2 more
doaj  

Twenty-two-year incidence trend of urological cancers in the Republic of Korea: 1999–2020 [PDF]

Investigative and Clinical Urology
Purpose: Cancer is a disease with high social costs, and policymaking through accurate statistics is very important. This study presents the national cancer statistics on the incidence of urological cancers in the Republic of Korea over 22 years, from ...
Seunghyeon Cho, Won-Ju Park
doaj   +1 more source

A comprehensive review of current knowledge on penile squamous cell carcinoma

Frontiers in Oncology
Neoplasm of the penis is relatively rare in most regions representing 0-2% of cancers worldwide. While the penis can be affected by sarcomas, basal cell carcinomas or even melanoma, Penile Squamous Cell Carcinoma (PSCC) represents approximately 95% of ...
Nishanth Thumma, Neharaj Pitla, V. Gorantla, Maira du Plessis   +3 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

Fluoroscopic-Guided Bilateral Superior Hypogastric Plexus Neurolysis in the Treatment of Intractable Neoplasm-Related Penile Pain [PDF]

, 2021
Kristy A Fisher, Janet Daoud, Christian D. Gonzalez, Jessica Reyes, Daniel J. Lopez, Oleg Desyatnikov   +5 more
openalex   +1 more source

Local treatment with electrochemotherapy of superficial angiosarcomas: Efficacy and safety results from a multi-institutional retrospective study [PDF]

, 2016
Background: Angiosarcoma is an aggressive vascular neoplasm with a high propensity for local recurrence. Electrochemotherapy is an emerging skin-directed therapy, exerting prominent cytotoxic activity, and antivascular effects.
Bonadies, CARLO ALBERTO, Bucher, S, Cabula, C, Campana, Lg, Curatolo, Pietro, Grilz, G, Guida, M, Rossi, C. r., Rotunno, Roberta, Santoriello, Andrea, Solari, N, Strippoli, S, Valpione, S   +12 more
core   +1 more source

Features of the clinical course of penile cancer

Andrology and Genital Surgery
Introduction. Penile cancer (PC) is one of the rare tumors, accounting for 1-2% of all neoplasms of the genitourinary system. The clinical course of the cancer process raises many questions among both urologistsoncologists in hospitals and outpatient ...
T. Nazarov, P. Shcheplev, N. Naumov, P. Karlov, I. V. Rychkov, S.S. Vodopyan, V. Gavrilov, A.D. Krassilnikov, S. A. Vinnichuk   +8 more
semanticscholar   +1 more source