Results 141 to 150 of about 1,379,632 (255)

Cancer‐Associated Fibroblast‐Derived Sphingosine‐1‐Phosphate Activates a MALL–SDC4 Axis to Facilitate Perineural Invasion in Pancreatic Cancer

Advanced Science, EarlyView.
CAF‐derived S1P activates the S1PR3‐JNK‐Jun signaling pathway, thereby transcriptionally upregulating MALL expression in cancer cells. MALL increases the cell‐surface abundance of SDC4 by promoting its recycling and restricting its lysosomal degradation, which in turn enhances RhoA‐p‐MLC2‐dependent amoeboid invasion and SDC4‐PTN axis‐mediated cancer ...
Wang Peng, Mengdie Cao, Hai Huang, Shuya Bai, Luyao Liu, Jingwen Liang, Haochen Cui, Qiaodan Zhou, Shiru Chen, Jiamei Jiang, Luoxia Liu, Zhou Luan, Wei Chen, Si Xiong, Ronghua Wang, Bin Cheng, Yuchong Zhao   +16 more
wiley   +1 more source

Dutchified English in an Ohio Beachy Amish-Mennonite Community

The Journal of Amish and Plain Anabaptist Studies, 2019
This article compares the English spoken by Beachy Amish-Mennonites just outside the Holmes County, OH, plain community with the English of non-plain neighbors.
Lara Downing
doaj  

Thirty-fifth annual announcement of the Woman's Medical College of Pennsylvania, North College Avenue and Twenty-First Street, Philadelphia. Session of 1884-85.

, 1884
An annual announcement discussing the Woman's Medical College of Pennsylvania administration, faculty, and their roles at the ...
Woman's Medical College of Pennsylvania
core  

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Thirty-third annual announcement of the Woman's Medical College of Pennsylvania, North College Avenue and Twenty-First Street, Philadelphia. Session of 1882-83.

, 1882
An annual announcement discussing the Woman's Medical College of Pennsylvania administration, faculty, and their roles at the ...
Woman's Medical College of Pennsylvania
core  

Spike‐Embedded Nanocatalysts via Metal‐Directed Carbonization for Highly Efficient and Robust Semi‐Hydrogenation

Advanced Science, EarlyView.
A metal‐directed carbonization strategy transforms hierarchical organic microspheres into spiky carbon catalysts with Pd nanoparticles embedded at the tips. This approach resolves the activity‐stability trade‐off, achieving exceptional poison resistance in semi‐hydrogenations, offering a versatile, scalable platform for designing high‐performance ...
Yintao Li, Yang Sun, Minghang Li, Wenxuan Zhang, Zhengtao Li, Yihao Ni, Yao Zhang, Yong Wang, Samuel S. Veroneau, Pengfei Ji   +9 more
wiley   +1 more source

Forty-third annual announcement of the Woman's Medical College of Pennsylvania: North College Avenue and Twenty-First Street, Philadelphia. Session of 1892-93

, 1892
An annual announcement discussing the Woman's Medical College of Pennsylvania administration, faculty, and their roles at the ...
Woman's Medical College of Pennsylvania
core  

Colossal Photovoltaic Current in Ferroelectric Oxide by Constructing Defect Band

Advanced Science, EarlyView.
Colossal photovoltaic current density of 34.36 mA/cm2 under 375 nm illumination has been achieved in the Pb‐deficient PbTiO3 film. The ultraviolet photoresponsivity surpasses that of all reported ferroelectric materials. This enhancement is attributed to the junction effect between the Pb‐deficient and non‐defective layers.
Yiran Sun, Zhenbang Dai, Xingzhong Cao, Peng Zhang, Chen Lin, Zihang Huang, Ruian Zhang, Yi Fu, Xuanyu Jiang, He Tian, Jingjing Xue, Kaifeng Wu, Junhui Wang, Tianqi Deng, Andrew M. Rappe, Gaorong Han, Zhaohui Ren   +16 more
wiley   +1 more source

Type 2 diabetes mellitus and the cardiometabolic syndrome: impact of incretin-based therapies

Diabetes, Metabolic Syndrome and Obesity, 2010
Stanley Schwartz1, Benjamin A Kohl21Department of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Department of Anesthesiology and Critical Care, School of Medicine, University of Pennsylvania ...
Schwartz S
doaj  

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source